INTRODUCTION hematopoietic stem cell transplantation (HSCT) is associated with more respiratory infections due to immunosuppression. OBJECTIVE this study aimed to verify the frequency of rhinosinusitis after HSCT, and the association between rhinosinusitis and chronic graft vs. host disease (GVHD) and type of transplantation, clinical treatment, surgical treatment, and survival. METHODS thi...

UNLABELLED In patients with acute bacterial rhinosinusitis severe orbital and intracranial complications can occur. This review will illustrate the anatomic relationship between the paranasal sinuses and the orbital and intracranial compartments. Subsequently, the spectrum of orbital and intracranial complications of rhinosinusitis and related imaging findings will be discussed and illustrated ...

BACKGROUND Recent otolaryngologic studies document significant fatigue and bodily pain (BP) in patients with chronic rhinosinusitis. Studies of general medical patients are lacking. METHODS A case-control study of 297 consecutive general medical outpatients. RESULTS Sixty-five patients noted unexplained chronic fatigue (UCF), 33 reported BP, and 26 had both. Compared with 232 patients witho...

Radiological diagnosis forms an important tool in the armamentarium to diagnose and classify fungal rhinosinusitis. However, many times, the appearances may be deceptive; while on one hand in Allergic Fungal Rhinosinusitis the appearance is classical and considered one of the clinchers in the diagnosis of the condition, in invasive fungal rhinosinusitis (especially in the early phases), the app...

Patients with HIV/AIDS can present with multiple types of fungal rhinosinusitis, fungal balls, granulomatous invasive fungal rhinosinusitis, acute or chronic invasive fungal rhinosinusitis, or allergic fungal rhinosinusitis (AFRS). Given the variable spectrum of immune status and susceptibility to severe infection from opportunistic pathogens it is extremely important that clinicians distinguis...

Chronic sphenoid rhinosinusitis is a spectrum of inflammatory diseases in isolated sphenoid sinus which may persist over a period of 12 weeks. It is a different entity from other types of rhinosinusitis because clinical presentations include headache, visual loss or diplopia, and patients may or may not have nasal obstruction or nasal discharge. Nasal endoscopic examination is useful, and compu...

OBJECTIVES Yellow nail syndrome (YNS) is a rare disease of unknown cause characterized by the triad of yellow nails, respiratory manifestations, and lymphedema. Although several therapies for YNS have been reported, there is no common consensus in the treatment. In this case report, we present a case of 56-year-old woman with YNS, whose nail manifestation was dramatically improved after endosco...

Multiple studies indicated that chronic rhinosinusitis is associated with a dramatic reduction in patient quality of life. The presence of asthma and atopy may have cumulative and negative impact on quality of life. To assess quality of life, specific and generic questionnaires may be used. Specific questionnaires are usually focused on one particular area such as a disease state, a selected po...

OBJECTIVES To investigate the up-regulation of chemokine ligand 20 (CCL20) in chronic rhinosinusitis mucosa and to localize the distribution of CCL20 in the human paranasal sinus mucosa. DESIGN Prospective study. SETTING Tertiary academic institution. PATIENTS Ten patients who underwent functional endoscopic sinus surgery for chronic rhinosinusitis without nasal polyps and 10 normal contr...

Chronic rhinosinusitis (CRS) is one of the most common persistent disorders developed world, requiring input from various specialists including primary care physicians, otolaryngologists, respiratory and allergologists. B-cell lymphoproliferative (BLPDs) are a heterogenous group malignant conditions defined by an accumulation mature B lymphocytes in bone marrow, blood, lymphoid tissues. We pres...