This experiment was conducted, during a seven-week period to investigate, the effects of using various levels of garlic cloves and turmeric rhizome powders, on laying hens’ performance, egg quality characteristics and cholesterol content in yolk. Two hundred and sixteen, 27-weeks old Novogen white laying hens were assigned randomly into nine treatments with eight replicates of three birds each....

BACKGROUND Pentanisia prunelloides is a medicinal plant widely used to remedy various ailments including infections, fever and rheumatism in Eastern Cape Province of South Africa. There is scanty report on the phytochemical and biological properties of the plant; hence various solvent extracts of the dried plant materials were phytochemically screened, and its aqueous extract evaluated for acut...

Alzheimer's disease (AD) is an age-related neurodegenerative disease, affecting over 20 million people worldwide. Until recently, two major hypotheses were proposed regarding the molecular mechanism of pathogenesis: the cholinergic hypothesis and the amyloid cascade hypothesis. At present, acetylcholinesterase inhibitors are the most effective the...

TCM materials are normally processed before being used clinically, and different processing methods lead to different medicinal effects. The Chinese Pharmacopoeia1 lists three processing methods for Coptidis Rhizoma. Coptidis Rhizoma processed by rice wine is used for toothache and conjunctivitis, while that processed by ginger juice or the extract of Corni Fructus is used as an anti-emetic and...

A simple method was established to determine protoberberine alkaloids in Cortex Phellodendri and Rhizoma Coptidis based on an acidic potassium permanganate chemiluminescence (CL) system. The optimum conditions for the CL reaction between protoberberine alkaloids and potassium permanganate were studied in detail. Under the optimum conditions, the linear response ranges for berberine, palmatine a...

splenectomy, and it should not be used at all in patients with glucose-6phosphate dehydrogenase deficit. Rhizoma coptidis and its main alkaloid component, berberine, inhibit the proinflammatory activity induced by tumor necrosis factor-alpha (TNF-α)2 in a dose-dependent manner. Recent studies have investigated the antiacne properties of various groups of Chinese herbs—some containing Rhizoma co...

BACKGROUND Jiao-Tai-Wan (JTW), composed of Rhizome Coptidis and Cortex Cinnamomi, is a classical traditional Chinese prescription for treating insomnia. Several in vivo studies have concluded that JTW could exert its therapeutical effect in insomnia rats. However, the specific mechanism is still unclear. The present study aimed to explore the effect of JTW on sleep in obesity-resistant (OR) rat...

Cardiovascular diseases (CVDs) are among the leading causes of morbidity and mortality in both the developed and developing world. Rhizoma coptidis (RC), known as Huang Lian in China, is the dried rhizome of medicinal plants from the family Ranunculaceae, such as Coptis chinensis Franch, C. deltoidea C.Y. Cheng et Hsiao, and C. teeta Wall which has been used by Chinese medicinal physicians for ...

AIM OF STUDY To investigate the inhibitory effect of Coptidis rhizome aqueous extract (CRAE) on vascular endothelial growth factor (VEGF) expression and tumor angiogenesis in hepatocellular carcinoma (HCC). METHODS Quality control of CRAE was determined. Secretion of VEGF protein and expression of its mRNA in MHCC97L and Hep G2 cells were measured with enzyme-linked immunosorbent assay and qu...