background the ala of the nose, with its particular texture and characteristics, poses both aesthetically and functionally intriguing challenges and is rather problematic regarding choices for reconstructive methods. both flaps and grafts have been used to restore natural structure of nasal ala. the present study summarizes a ten-year experience of reconstructive surgery using small composite g...

A suitable qualification module for rain intensity measurement instruments is proposed based on an automatic procedure for dynamic calibration of traditional Tipping Bucket Raingauges (TBRs). Following an initial background of dedicated laboratory tests, which assisted in producing reference calibration curves for various types of commercial gauges from different manufacturing companies, the ef...

in the asemi-gawa area of intermediate high-pressure and low-temperature sanbagawa metamorphic belt in central shikoku, japan, piemontite-quartz schists are common in which cation exchange between piemontite and garnet has been studied. piemontite in contact with garnet usually contains two zones in which core is enriched in mn3+ and surrounded by a rim rich in fe3+. garnet is ca-fe-bearing spe...

Rab3 interacting molecules (RIMs) are evolutionarily conserved scaffolding proteins that are located at presynaptic active zones. In the mammalian nervous system, RIMs have two major activities that contribute to the fidelity of baseline synaptic transmission: they concentrate calcium channels at the active zone and facilitate synaptic vesicle docking/priming. Here we confirm that RIM has an ev...

Synaptic communication requires the controlled release of synaptic vesicles from presynaptic axon terminals. Release efficacy is regulated by the many proteins that comprise the presynaptic release apparatus, including Ca(2+) channels and proteins that influence Ca(2+) channel accumulation at release sites. Here we identify Drosophila RIM (Rab3 interacting molecule) and demonstrate that it loca...

We report that herpes simplex virus type 1 (HSV-1) infection leads to the recruitment of protein kinase C (PKC) to the nuclear rim. In HEp-2 cells, PKC recruitment to the nuclear rim was initiated between 8 h and 12 h postinfection. PKCdelta, a proapoptotic kinase, was completely recruited to the nuclear rim upon infection with HSV-1. PKCalpha was less dramatically relocalized mostly at the nuc...

This study compiled a wide range of modern and historic geospatial datasets to examine ecological and geomorphic change at Diego Garcia Atoll across a 38-year period (1967–2005). This remarkable collection of spatially referenced information offered an opportunity to advance our understanding of the nature and extent of environmental change that has taken place with the construction of the mili...