The Rho family GTPases function as key molecular switches, controlling a variety of actin-dependent cellular processes, such as the establishment of cell polarity, cell morphogenesis, and movement in diverse eukaryotic organisms. A novel subfamily of Rho GTPases, Rop, has been identified in plants. Protein gel blot and RNA gel blot hybridization analyses indicated that one of these plant Rho GT...

A critical step in the life cycle of many fungal pathogens is the transition between yeast-like growth and the formation of filamentous structures, a process known as dimorphism. This morphological shift, typically triggered by multiple environmental signals, is tightly controlled by complex genetic pathways to ensure successful pathogenic development. In animal pathogenic fungi, one of the bes...

Herein we characterized various genetic markers and the biological behavior of a natural recombinant strain of Toxoplasma gondii (P-Br). From nine genetic markers analyzed, three (B1, ROP1, and SAG1) and three (cS10-A6, GRA6, and SAG3) markers belong to parasites from the type I and type III lineages, respectively. The SAG2 and L363 loci were shown to be type I-III chimera alleles. The cB2l-4 m...

Literák I . , I . Rychl ík: Genome Changes in the Toxoplasma gondii Strains During Laboratory Passages in Mice. Acta Vet. Brno 1999, 68: 203–208. Three strains of Toxoplasma gondii isolated from rabbits (K6 and K9) and a cat (K24) in the Czech Republic in 1994-95 were maintained in a tissue cyst form in laboratory mice by injections of brain homogenate every 4 6 months. These strains were passa...

Microtubules have important roles in intracellular trafficking. The targeted transport of cellulose synthase along microtubule tracks determines the orientation of cellulose microfibrils and hence influences cell shape and elongation (Lloyd, 2006; Paredez et al., 2006). The ability of microtubules to alter their cellular layout in response to various stimuli is central to their function. In the...