Abstract Background Rheumatoid arthritis (RA) is an autoimmune disease in which the immune system attacks tissues of joints by mistake. Different factors—either genetic or environmental—affect development RA patients. A lot studies aimed to examine associations with this different populations. This research aspires perform a association study between six single-nucleotide polymorphisms (SNPs) a...

We conducted a case-control study to investigate genetic variants of miR-146a rs2910164, miR-196a2 rs11614913, miR-149 rs2292832 and miR-499 rs3746444 in the development of HCC in a Chinese population. This case-control study included 266 HCC patients and 266 control subjects between January 2012 and December 2013. Conditional logistical regression analysis indicated that TT genotype and T alle...

objective(s): accumulating evidence has demonstrated that mirnas contribute to various genetic and epigenetic modifications in the pathogenesis of gastric cancer (gc). recent studies focused on the four single nucleotide polymorphisms (snps) of pre-mirnas including rs11614913, rs3746444, rs2910164, and rs2292832. it was suggested that these four snps were significantly associated with the risk ...