Streptomyces clavuligerus is a member of the Actinobacteria family primarily known for its production clavulanic acid antibiotic. The need identification new antimicrobials led to volatile components S. metabolites using GC-MS. isolate was obtained from Ocimum gratissimum rhizosphere starch casein agar, and identified molecular typing. preliminary antibacterial screening carried out some indica...

The paper argues for the importance of utterances (as opposed to \sen-tences in context") as basic units in dialogue. The main case study is clar-iication: a characterization is provided within KOS, a recently developed synthesis of situation semantics and dialogue games, of the clariications that can follow up on an utterance. This involves outlining: (a) a theory of understanding for dialogue...

NAD-dependent l-glutamate dehydrogenase (NAD-GDH) activity was detected in cell extract from the psychrophile Janthinobacterium lividum UTB1302, which was isolated from cold soil and purified to homogeneity. The native enzyme (1,065 kDa, determined by gel filtration) is a homohexamer composed of 170-kDa subunits (determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis). Consiste...

We announce the sequencing of Streptomyces chartreusis NRRL 12338 and NRRL 3882 and Streptomyces lysosuperificus ATCC 31396. These are producers of tunicamycins, chartreusins, cephalosporins, holomycins, and calcimycin. The announced genomes, together with the published Streptomyces clavuligerus genome, will facilitate data mining of these secondary metabolites.

Benzylpenicillin, a typical antibiotic produced by some species of fungi, was obtained by direct cyclization of the heteropeptide phenylacetyl-L-cysteinyl-D-valine using cell-free extracts of Streptomyces clavuligerus. This is the first description of evidence of the synthesis of benzylpenicillin from a non natural molecule using a bacterial enzyme.