malignant peripheral nerve sheath tumor (mpnst), the principle malignancy of peripheral nerve origin, though rare in the general population, occurs with excessive frequency among patients with neurofi bromatosis. this tumor always arises in soft-tissues, usually found in the lower extremities and only 10-12% of all lesions occur in the head and neck region, which makes it a rare entity. the pri...

objective(s):  cd44 is a member of the cell adhesion molecules family. naturally, cd44s, along with cd44v3 influence the cell motility, migration, and adhesion, while in tumor cells they lead to tumor invasion, progression, and metastasis. the purpose of this research is to evaluate the cd44s and cd44v3 expression in esophageal squamous cell carcinoma (escc) and to reveal their correlations wit...

Background: Granular cell tumor (Abrikossoff’s tumor) is a rare and slow-growing tumor of the soft tissue. Originated from the Schwann cells, it is often a benign tumor, but it can be malignant in 1-3% of the cases. Malignant cases can cause significant morbidity and mortality. It may develop in many anatomic locations, especially in the head and neck region, and also in skin and subcutaneous t...

Paget’s disease of the nipple is an unusual manifestation of breast cancer. Most cases of mammary Paget`s disease are associated with an invasive or in situ breast tumor, even with no mass observed in mammography imaging. Very rarely does Paget’s disease occur in the absence of any underlying neoplasia .Herein, we report an 82-year-old woman with an unusual presentation of mammary Paget’s disea...

ebv-carrying human cell lines, depending on whether the cells are derived from burkitt's lymphoma (bl) tumor biopsies or transformed by ebv in vitro, have different growth properties in vitro. in contrast, there are no clear differences between tamarin tumor lines and tamarin lcls in vitro. both types of tamarin cell lines could grow in agarose and formed colonies unlike human lcls, althou...