Dissolved oxygen (DO) is an important influencing factor in the process of aerobic microbial fermentation. Spinosad is an aerobic microbial-derived secondary metabolite. In our study, spinosad was used as an example to establish a DO strategy by multi-scale analysis, which included a reactor, cell and gene scales. We changed DO conditions that are related to the characteristics of cell metaboli...

Two formulations of spinosad, direct application tablet (DT) and 0.5% granules (GR), at 3 dosages (0.25, 0.5 and 1.0 mg/l) in 200-liter earthen jars were evaluated against the larvae of Aedes aegypti. Two water regimens were used in the jars: jar full all the time and a full jar in which half the volume of the water was removed and replaced at each assessment interval. All treatments and contro...

Therapeutic effect of ethanolic extract of Hygrophila spinosa in gentamicin-induced nephrotoxic model of kidney injury in male Sprague-Dawley rats was studied. Rats were administered with gentamicin at a dose of 80 mg/kg intraperitoneally (ip) to induce nephrotoxicity. Kidney function was assessed by measuring serum creatinine and urea. Kidney superoxide dismutase, lipid peroxidation, catalase ...

Animals that possess extreme sensory structures are predicted to have a related extreme behavioural function. This study focuses on one such extreme sensory structure-the posterior median eyes of the net-casting spider Deinopis spinosa. Although past research has implicated the importance of vision in the nocturnal foraging habits of Deinopis, no direct link between vision in the enlarged eyes ...

Mosquito larvicides derived from microbial organisms and insect growth regulators have been increasingly used to control mosquito larvae worldwide. Their relative target specif‐ icity, nontarget safety, and environmentally friendly profile have been well documented. The current chapter was intended to review and analyze the relevant information regard‐ ing resistance development and resistance ...

BACKGROUND The main objective was to evaluate the possible protective effect of Chuquiraga spinosa extract on N-methyl nitrosourea (NMU)-induced prostate cancer in rats and DU-145 cell line. MATERIALS AND METHODS Prostate carcinogenesis was induced in 30 male Holtzman rats by providing cyproterone acetate, testosterone, and NMU. The tumors were monitored and hematological and biochemical para...

Due to the use of Cleome spinosa Jacq. (Cleomaceae) in traditional medicine against inflammatory and infectious processes, this study evaluated the in vitro antimicrobial potential and phytochemical composition of extracts from its roots and leaves. From leaves (L) and roots (R) of C. spinosa different extracts were obtained (cyclohexane: ChL and ChR; chloroform: CL and CR; ethyl acetate: EAL a...