OBJECTIVE Cancer represents the second cause of mortality in the world. Saffron as a medicinal plant is known for its anti-cancer and anti-depressant properties. In this randomized double blind clinical trial, the effects of saffron on response to treatment in patients suffering from liver metastasis were evaluated. MATERIALS AND METHODS Thirteen patients suffering from liver metastases who r...

BACKGROUND The progressive nature of glaucoma and its growing incidence make its therapy an important target for research. The role of oxidative damage in the pathogenesis of glaucoma makes antioxidants such as saffron extract an attractive target for potential clinical use. Herein, we evaluate the effect of aqueous saffron extract on intraocular pressure (IOP) in eyes with primary open-angle g...

Background & Aim: Saffron is one of the expensive spices known since antiquity for its color, flavor and medicinal properties. Saffron is the dried stigma of crocus sativus plant. The three basic components of the stigma on which the qualitative characteristics of Saffron depend are crocin (color), picrocrocin (taste), and safranal (aroma). The quality of saffron is a ...

Moroccan saffron is mainly produced in the South, on a limited zone of about 600 ha. In 2005, the National Institute of Agronomic Research, Morocco, carried out a study on trying saffron crop in some underprivileged regions under diverse environments, as way to propose alternative crop for the socio-economic development of rural area. The preliminary results obtained during this first year are ...

BACKGROUND Due to safety concerns and side effects of many antidepressant medications, herbal psychopharmacology research has increased, and herbal remedies are becoming increasingly popular as alternatives to prescribed medications for the treatment of major depressive disorder (MDD). Of these, accumulating trials reveal positive effects of the spice saffron (Crocus sativus L.) for the treatme...

saffron is an important spice values for its color, aroma and flavor in the food industry. a significant proportion of saffron compound is lost during processing and storage because of its volatility and sensitivity to oxidation. thepresent research microencapsulated saffron color compounds (crocin) by freeze drying. the freeze-dried aqueous saffron effective compound extract was first prepared...

Direct selective detection of erythrosine in saffron in the presence of other synthetic dyes considers its fluorescence at 532 nm excitation/548 nm emission. Saffron pre-treatment was according to the ISO 3632-2 trade standard test methods. On account of calculated quantum yield values, none of the yellow dyes is expected to interfere. Among red ones, reservations about allura red AC, azorubine...

Background and Objective Drug dependence is one of the serious problems around the world. Saffron is one of those beneficial medicinal plants which is embedded with a similar mechanism to methadone (e.g., inhibition of serotonin reuptake). Thus, it can be helpful in reducing the withdrawal symptoms. The aim of this study was to reduce the daily dose of methadone usage and reduce its side effect...

Diabetic encephalopathy is one of the severe complications in patients with diabetes mellitus. Findings indicate that saffron extract has antioxidant properties but its underlying beneficial effects on diabetic encephalopathy were unclear. In the present study, the protective activities of saffron were evaluated in diabetic encephalopathy. Saffron at 40 and 80 mg/kg significantly increased body...

This study evaluated the possible protective effect of Crocus sativus L. (saffron) in the treatment of renal calculi. Aqueous extract of saffron (25, 50 and 100 mg/kg, daily) was administered intraperitoneally in two regimens of protective or curative, using male Wistar rats. Urolithiasis was induced by ethylene glycol (% 0.75) in drinking water. Urine was collected for biochemical analysis and...