Angela Verne. (Catholic Printing Company, Farnwort'1' Bolton, Lanes. 18s.) "According to legend, she (St. Dymphna) fled from Ireland to Gheel with the priest Gonerbernus to escape the unholy desire of her own father, a pagan kl0fc of Ireland. The latter, however, discovered their whereabouts and put them ^ death." These stark sentences, which embody all that is known of the patron sain of the f...

Rovers C, Netea MG, Bont N de, Demacker PNM, Jacobs C, Kullberg BJ, Meer JWM van der, Stalenhoef AFH. LPS-induced cytokine production and expression of J-2 integrins and CD-14 by peripheral blood mononuclear cells of patients with homozygous familial hypercholesterelemia. Atherosclerosis 1998; 141: 99-105. Sain-van der Velden MG de, Reijngoud DJ, Kaysen GA, Gadellaa MM, Voorbij H, Stellaard F, ...

Insulin receptor substrate-1 (IRS-1) is a multi-domain protein that mediates signal transduction from receptors for insulin and other growth factors to a variety of downstream molecules through both tyrosine-phosphorylation-dependent and -independent interactions. While the tyrosine-phosphorylation-dependent interactions mediated by IRS-1 have been well characterized, the molecular basis underl...