A new approach to sample handling for powder X-ray diffraction analysis is presented that allows characterization of poorly prepared samples. The technique relies on vibrations generated in a sample holder to create movement of the powdered sample in the absence of macroscopic movement of the sample holder itself. The major benefits over conventional sample handling strategies are: 1) the abili...

Foodstuffs analysis is very important due to population growth and increasing consumer demand for safety and nutritional excellence. The Analysis of different compounds in foodstuffs is so difficult without using sample preparation techniques. Traditional techniques require large amounts of toxic organic solvents. As a result, they are not only expensive but also environmentally unfriendly and ...

Sample Preparation for the Relative Quantitation of Protein Abundance Sample Preparation for Monitoring Components of a Protein Complex Sample Preparation for Relative Quantitation of Posttranslational Modifications Sample Preparation for the Identification of Tyrosine Kinase Substrates Electrophoresis and Silver Staining of Polyacrylamide Gels In-Gel Trypsin Digestion Reversed Phase Column Pre...

Nerviano Medical Sciences (NMS) is a new company created following the spin-off by Pfizer of their R&D centre in Nerviano (Milan, Italy). Through its Preclinical Development (PCD) unit, NMS specialises in toxicology, drug metabolism and pharmacokinetics services to pharmaceutical and biotechnology companies. These PCD capabilities are used to support the selection of candidate drugs, predict cl...

Western blotting is an analytical technique used to detect specific proteins in a given sample of tissue homogenate or extract. It uses gel electrophoresis to separate native or denatured proteins by the length of the polypeptide (denaturing conditions) or by the 3-D structure of the protein (native/ non-denaturing conditions). The proteins are then transferred to a membrane (typically nitrocel...