The chain graph sandwich problem asks: Given a vertex set V , a mandatory edge set E1, and a larger edge set E2, is there a graph G= (V ,E) such that E1 ⊆ E ⊆ E2 with G being a chain graph (i.e., a 2K2-free bipartite graph)? We prove that the chain graph sandwich problem is NP-complete. This result stands in contrast to (1) the case where E1 is a connected graph, which has a linear-time solutio...

The recent invasion of southern California by the glassy-winged sharpshooter (GWSS), Homalodisca coagulata (Say) (Hemiptera: Cicadellidae), has triggered a statewide control eVort. Management of GWSS will include biological control using resident and imported natural enemies. Currently, very little information is available on the role of generalist predators in suppression of GWSS eggs, nymphs ...

The ability of Bacillus cereus to cause foodborne toxicoinfections leads to increasing concerns regarding consumer protection. For the diarrhea-associated enterotoxins, the assessment of the non-hemolytic enterotoxin B (NheB) titer determined by a sandwich enzyme immunoassay (EIA) correlates best with in vitro cytotoxicity. In general, the regulation of enterotoxin expression of B. cereus is a ...

BACKGROUND Hepcidin, a key regulator of iron metabolism, binds to the iron transporter ferroportin to cause its degradation. In humans, hepcidin deficiency has been linked to hemochromatosis and iron overload, whereas increased concentrations have been reported in anemia of cancer and chronic disease. There is currently an unmet clinical need for a specific immunoassay with a low limit of quant...

The coupling of model batteries and surface-sensitive techniques provides an indispensable platform for interrogating the vital surface/interface processes in battery systems. Here, we report a sandwich-format nanopore-array using ultrathin graphite electrode anodized aluminum oxide (AAO) film. porous framework AAO regulates contact pattern electrolyte with from inner side, while minimizing con...

The aim of this work is to evaluate the influence of fabrication methods on the com-pressive properties of sandwich composites using both experimental work and numerical simulations. Two types of sandwich composites with E-glass/Kevlar/polyester resin facings and End-grain balsa wood as core have been produced by vacuum infusion processing (VIP) and hand-lay up (HL) method. Compression tests on...

This study is limited to study of buckling analysis of a sandwich cylindrical shell with functionally graded face sheets and homogenous core. High-order sandwich plate theory is improved by considering the in-plane stresses of the core that usually are ignored in the analysis of sandwich structures. Assume that all properties of the face sheets and the core are temperature dependent. Strain com...

OBJECTIVES Non-invasive tests for early detection of lung cancer are an important unmet clinical need. CIZ1b plasma biomarker can discriminate stage 1 lung cancer from within high-risk groups with clinically useful accuracy, with ROC AUCs in excess of 0.9 for two independent retrospective cohorts, and could therefore meet this need. Our aim was to characterise the native state of the biomarker ...

We demonstrate rapid single-nucleotide polymorphism (SNP) genotyping on a poly(dimethylsiloxane)-glass microchip. Sandwich-type affinity electrophoresis was employed to achieve sufficient specificity for reliable genotyping of unpurified PCR products. We tested three SNPs in different genes: CYP2D6 of artificial templates, and ALDH3A1 and CYP1A1 of human genomic samples. The target sequences we...