Flow cytometric analyses were performed to evaluate HLA-DR (+) activated T lymphocytes (Tact; CD3 (+)/CD4 (+)/CD25(medium)) and T regulatory cells (Treg; CD3 (+)/CD4(+)/CD25(high)) in the circulation of children 8-10 years of age living in an area endemic for both Plasmodium falciparum and Schistosoma mansoni in western Kenya. Those children with only S. mansoni had a higher mean percentage of ...

BACKGROUND Schistosoma mansoni was observed and reported in Kuluva hospital Arua District in north western Uganda as early as 1902. S. mansoni is widely distributed in Uganda along permanent water bodies. OBJECTIVE To review the litreture on scistosomiasis in Uganda, since 1902. METHOD The core literature for this short review was searched from reports and publications by the British coloni...

OBJECTIVE To determine the prevalence and intensity of schistosomiasis in urban and peri-urban Kariba. DESIGN A cross sectional schistosomiasis survey involving screening people for infection and searching for intermediate host snails. SETTING Lake Kariba Research Station, Zimbabwe. SUBJECTS One thousand and seventy three people living in four residential areas of Kariba were screened for...

BACKGROUND Colorectal cancer associated with chronic intestinal schistosomiasis has been linked with the chronic inflammation as a result of schistosomal ova deposition in the submucosal layer of the intestine. Among all species Schistosoma japonicum has been more linked to development of colorectal cancer as compared to Schistosoma mansoni due to absence of population-based studies to support ...

Schistosoma mansoni, which causes schistosomiasis has humans as the primary definitive host and mollusks Biomphalaria glabrata, B. straminea tenagophila intermediate hosts. The goal of this research was to undertake a malacological survey on watercourses in city Betim, using data provided by city´sHealth´s Department. were collected from pre-selected sites, examined for presence cercariae taxon...

Objective: Knowledge, attitudes and preventative practices of risk groups for neglected tropical diseases such as intestinal schistosomiasis are important aspects for their control. This study aimed to determine the prevalence of Schistosoma mansoni, knowledge, perceptions and preventative practices of school children towards schistosomiasis in the Sengerema district, Tanzania. Methods: We cond...

Background. Schistosomiasis is a public health problem in Democratic Republic of the Congo but estimates of its prevalence vary widely. The aim of this study was to determine prevalence of Schistosoma mansoni infection and associated risk factors among children in 4 health areas of Kisantu health zone. Methods. A cross-sectional study was carried out in 4 health areas of Kisantu health zone. 38...

The assessment of periportal fibrosis is of major importance in determining strategies, prognosis and risk for complications in schistosomiasis mansoni . For the last 2 decades, abdominal ultrasound has been used as the gold standard for the evaluation of liver fibrosis in schistosomiasis mansoni , because hepatic biopsy has been shown to have low sensitivity in diagnosing advanced schistosomia...

BACKGROUND Schistosoma mansoni and S. haematobium are co-endemic in many areas in Africa. Yet, little is known about the micro-geographical distribution of these two infections or associated disease within such foci. Such knowledge could give important insights into the drivers of infection and disease and as such better tailor schistosomiasis control and elimination efforts. METHODOLOGY In a...

BACKGROUND Studies in Sub Saharan Africa have shown that the Circulating Cathodic Antigen point-of-care-test (POC-CCA) is more accurate in the detections of S. mansoni than the microscopic Kato-Katz technique but less is known about the accuracy of this rapid test in detecting S. haematobium infections. This study was intended to evaluate the field accuracy of POC-CCA as a rapid test kit for sc...