objective(s): to investigate the effect of topical administration of alpha-lipoic acid into chitosan conduit on peripheral nerve regeneration using a rat sciatic nerve transection model. materials and methods: forty five wistar rats were divided into three experimental groups randomly. a 10-mm gap of sciatic nerve was bridged with a chitosan conduit following surgical preparation and anesthesia...

background: olfactory ensheathing glia (oeg) has been shown to have a neuroprotective effect after being transplanted in rats with spinal cord injury. this study was conducted to determine the possible beneficial results of olfactory mucosa transplantation (omt) which is a source of oeg on functional recovery and axonal regeneration after transection of the sciatic nerve. methods: in this study...

  Despite promising results observed using silicone rubber chamber, no previous comprehensive work was performed on behavior of the conduit. Present study aimed at further functional, histomorphometrical and immunohistochemical assessment of nerve regeneration in the same animal along a 10-mm rat sciatic nerve gap. Fifty- four male Wistar rats were divided into three experimental groups (n = 1...

background: many people suffer from nerve injury. the time consuming nature of the treatments makes the condition worse. therefore, finding a way to accelerate the process of nerve repair is very important. objective: to determine the effect of ultrasound on the acceleration of crushed peripheral nerve regeneration. methods: the experimental model included crushed rat’s sciatic nerve. 40 rats w...

Acetabular fracture is usually treated with osteosynthesis. However, in the case of an intra-articular fracture, osteosynthesis can result in arthropathy of the hip joint and poor long-term results, hence, total hip arthroplasty is required. However, in total hip arthroplasty for postoperative acetabular fracture, sciatic nerve palsy tends to develop more commonly than after primary total hip a...

The Effects of pH Gradients on the Action of Procaine and Lidocaine in Intact and Desheathed Sciatic Nerves. GEORGE E. STROBEL AND C. PAUL BIANC1II 1 The Effects of pH Gradients on the Uptake and Distribution of C14-Procaine and Lidocaine in Intact and Desheathed Sciatic Nerve Trunks. GEORGE E. STROBEL AND C. PAULBIANCHI 18 Sites of Action of SKF 525-A in Nerve and Muscle. G. SUAREZ-KURTZ AND C...

Objective(s): The purpose of this study is to investigate the indication function of the calcium circulation-related factors on the damage to muscle strength and contraction function after nerve injury. The target factors include ryanodine receptor (RyR), inositol-1,4,5-triphosphate receptor (IP3R), phospholamban (PLN), cryptocalcitonin (CASQ), ATPase and troponin C (T...

Neurology lays many claims to being one of the more precise and scientific branches of medicine but, nevertheless, there have been several neurological conditions almost mediaeval in their conceptions. One of these is a group included under the general heading of the neuritides-namely, sciatic and brachial neuritis and neuralgia. There is now a large body of evidence to show that the humoral, a...

objective: the aim of present study was to evaluate the effects of oral administration of gallic acid (ga) for 21 days alone and in combination with exercise on nerve conduction velocity and sensory and motor functions in rats with sciatic nerve crush. materials and methods: seventy adult male wistar rats (250-300 g) were divided randomly into 7 groups with 10 in each: 1) control (cont), 2) cru...

Background: Although several anterior approaches to sciatic nerve block have been described, they are used infrequently. The authors describe a new anterior approach that allows access to the sciatic nerve with the patient in the supine position. Method: Sciatic nerve blocks were performed in 22 patients. A line was drawn between the inferior border of the anterosuperior iliac spine and the sup...