The Cover Feature shows a scorpion amongst colony of A. baumannii bacteria. We can see that the bacteria bear our target pentasaccharide (depicted here using “sugar code” notation) and one these pentasaccharides adorns scorpion′s stinger. this as an apt symbol for role plays in virulence during infection. Nevertheless, we shadow stinger looming ominously over legion baumannii. Might which ensur...

background: scorpion sting is a public health problem in khuzestan, south-west iran. the aims of the current study were to monitor the hospitalized children, due to scorpion sting, and releasing more clinical and epidemiologic data related to scorpionism in this province. methods: in this retrospective study, the data of scorpion sting victims, among the hospitalized children in abuzar children...

[3H]Saxitoxin binds to a single class of receptor sites in rat brain synaptosomes and in broken membrane fractions derived from rat brain with a KD of approximately 2 11~ at 36°C. Batrachotoxin and scorpion toxin, which act at different receptor sites to activate sodium channels, have no effect on saxitoxin binding. Osmotic lysis and depolarization also have no effect on saxitoxin binding. Thes...

Scorpion bite is common in rural areas of India with self limiting local reaction and pain at envenomation site, however envenomation due to Mesobuthus tamlus (Indian red scorpion) some time have uncommon systemic manifestation like myocarditis, pulmonary edema, pancreatitis, defibrination syndrome, DIC and CNS manifestation due to hemorrhagic infarct, all these systemic manifestation is corrob...

Scorpion venom contains a variety of biologically active peptides. Among them, neurotoxins are major components in the venom, but it also peptides that show antimicrobial activity. Previously, we identified three insecticidal from Liocheles australasiae scorpion, activities and structures other remained unknown. In this study, performed transcriptome analysis gland scorpion L. to gain comprehen...

Venom of the scorpion Leiurus quinquestriatus acts cooperatively with the alkaloids veratridine, aconitine, and batrachotoxin in activating the action potential Na+ ionophore. A small (Mr = 6700), basic (pI approximately 9.8), toxic polypeptide purified approximately 80-fold from this venom by ion exchange chromatography appears homogeneous by gel electrophoresis and isoelectric focusing and, l...

Death due to poisonous scorpion (Buthidae family) stings is a common event in the developing countries. Scorpion envenoming syndrome results in autonomic storm, release of catecholamines, angiotensin II, glucagon, glucocorticoids, either suppressed insulin secretion or hyperinsulinemia; hyperglycemia, lipolysis – sudden increase in free fatty acids (FFA), acute myocarditis, disseminated intrava...

BACKGROUND Death caused by scorpion envenoming is a common event in the tropical and subtropical countries including many regions in India. Severe scorpion envenoming causes an autonomic storm producing multi-system organ-failure (MSOF) and death. OBJECTIVES To determine the efficacy of Anti-scorpion venom serum (AScVS) in patients stung by scorpions (Mesobuthus tamulus concanesis Pocock--ear...

Scorpions belong to class arachnide and are quite commonly encountered in India. The scorpions venom containing short neurotoxin polypeptides consists of low molecular weight proteins, Which have mechanisms of lethal and paralytic effect. In many tropical and subtropical countries, venoms from medically important scorpion species are still used in the production of anti-venoms to the treatment ...

Scorpion envenomation is a life-threatening emergency and a common public health problem in children, especially during summer time in all regions of Turkey. Severe scorpion envenoming is characterized by cardiocirculatory failure which may lead to pulmonary edema. We aimed to evaluate clinical, laboratory, treatment and outcome characteristics for children with scorpion envenomation who requir...