A drop has been observed in the renal threshold for hemoglobin in dogs, of over 60 per cent, following repeated injections daily. It was not associated with a cessation of tubular reabsorption. Hemoglobin excretion rate curves, obtained initially and after lowering the threshold, have proved to be parallel lines originating at the respective levels. Hemoglobin containing radio-active iron has b...

The recent work of Kligman and Shelley (1) does much to advance our concepts of the physiology of sebaccous secretion. This paper presents several experimental observations that intend to further modify these concepts. The composition of scbum has been thoroughly explored. From an examination of its approximate composition, one would expect sebum to emulsify water as the internal phase of a wat...

We studied the effect of protein and protein-free energy intake on the degradation rate of myofibrillar protein in preruminant calves in two experiments. Both experiments were similar in design but were performed with two live weight ranges: 80 to 160 kg (Exp. 1) and 160 to 240 kg (Exp. 2). In each experiment, calves were allocated to either an initial slaughter group or to one of 12 treatments...

BACKGROUND Assessment of human exposure to non-persistent pesticides such as pyrethroids is often based on urinary biomarker measurements. Urinary metabolite levels of these pesticides are usually reported in volume-weighted concentrations or creatinine-adjusted concentrations measured in spot urine samples. It is known that these units are subject to intra- and inter-individual variations. Thi...

Multiple factors are involved in acne pathogenesis, and sebum secretion is one of the main ones. The role sebum plays in acne development has not been completely elucidated yet; however, increasing amounts of data seem to confirm the presence of alterations in sebum from acne patients. Altered ratio between saturated and unsaturated fatty acids has been indicated as an important feature to be c...

Background. Acne is a dermatosis that involves an altered sebum pattern. Objectives. (1) To evaluate if a treatment based on antibiotics (lymecycline) can alter fatty acids contents of the sebum of patients with acne; (2) to evaluate if oral supplementation of fatty acids can interfere with fatty acids contents of the sebum of patients with acne; (3) to evaluate if there is any interaction in f...