BACKGROUND An inadequate understanding of the complex morphologic characteristics of human filiform papillae has hampered the histopathological characterization of disorders affecting tongue keratinization. To better define the 3-dimensional cytoarchitecture of tongue epithelium, we performed detailed immunohistochemical analyses of normal and black hairy tongue tissues using a panel of antiker...

BACKGROUND At present, there are no guidelines on prevention and management of postpartum haemorrhage in primary midwifery care in the Netherlands. The first step towards implementing guidelines is the development of a set of quality indicators for prevention and management of postpartum haemorrhage for primary midwifery supervised (home) birth in the Netherlands. METHODS A RAND modified Delp...

A 13-month-old boy with recurrent upper respiratory infections, persistent fevers, and chronic rash presented to our facility. The patient had been treated with several months of antibiotics and topical creams with no improvement. In the emergency room, he had a prominent rash (panel A), jaundice, and tachypnea. Complete blood count showed white blood cells 3.5 3 10/mL, absolute neutrophils 0.3...