Current study was conducted to investigate antimicrobial activity of fruit extracts of two Solanaceous plants (Solanum nigrum and Solanum xanthocarpum) found in Pakistan. Petroleum ether, chloroform, dichloromethane, ethyl acetate, acetone, methanol and water were utilized for extraction. The highest percentages of polar components of both the species were extracted by water; little amount of n...

The methanolic leaf extract of Thuja occidentalis was evaluated for possible sedative activities in mice. Sedative activity was evaluated by using hole cross, open field, thiopental sodium-induced sleeping time and elevated-plus maze (EPM) tests at 200mg/kg and 400 mg/kg.  The extract decreased the locomotor activity of mice in hole cross, open field and EPM test and showed the remarka...

Gnagnan Solanum indicum L. The proximate composition includes crude fibre 8 wet.ABSTRACT Solanum nigrum black nightshade is widely used in ethnomedicine for its hepatoprotective, anti-proliferative, anti-inflammatory and anti-oxidative.Nanomaterials and Nanotechnology. Green Synthesis and Characterization of Biocompatible Gold Nanoparticles. Regular Paper.The fresh leaves of Solanum indicum sho...

asperugo procumbents l. has been used in iranian traditional medicine for the refreshing, tranquillizing and mood elevating activities. the present study was undertaken to evaluate the antidepressant and sedative-hypnotic potential of acute administration of the hydroalcoholic extract of this plant in mice.additionally, the effects of flumazenil on the hypnotic activity of the extracts were eva...

The sedative activity of eight aromatic natural medicines that are traditionally used in Japanese scent sachets was examined using an open field test with mice. Galangal (Kaempferia galanga), patchouli (Pogostemon cablin), sandalwood (Santalum album), spikenard (Nardostachys chinensis), cinnamon (Cinnamomum cassia), clove (Syzygium aromaticum), star anise (Illicium verum), and borneol (Dryobala...

Ethanol and other drugs of abuse modulate cAMP-PKA signaling within the mesolimbic reward pathway. To understand the role of the cAMP-PKA signal transduction in mediating the effects of ethanol, we have studied ethanol consumption and the sedative effects of ethanol in three lines of genetically modified mice. We report that mice with the targeted disruption of one Gsalpha allele as well as mic...

Anxiety is a most common emotional disorder affecting 20% of adult population worldwide. Eclipta alba is having memory enhancing quality & traditionally used for this purpose. Since paucity of data available for this clinical use, the present work was undertaken to study the anti anxiety & sedative effects of Ethanolic extract of leaves of Eclipta alba(EEEA) in albino rats using thiopental sodi...

The aim of this study was to determine the antioxidant activity as well as total phenol (TPC) and total flavonoid content (TFC) in two fruits, Solanum anguivi and Solanum incanum grown in Darjeeling Himalaya and used as vegetables in Nepali recipes. The antioxidant activities were examined by five different methods namely DPPH free radical scavenging activity, reducing power, iron chelation, an...

AIM To investigate methanol extracts of various parts of Rubus fruticosus L. (Rosaceae) for various neuropharmacological activities, such as anxiolytic, muscle relaxant, antidepressant, and sedative activities. MATERIALS AND METHODS The extracts were administered to albino mice orally at doses of 100, 300, and 500 mg/kg. The antidepressant activity was determined by using the forced swimming ...

In the present study, the metabolites present in the leaves of Solanum anguivi was extracted using ethyl acetate. HEpG-2 and MCF-7 cell lines were collected from NCCS. The ethyl acetate extract of the Solanum anguivi was analyzed for its antiproliferative activity against the cell lines using MTT assay at various concentrations. The cell viability was reduced upto 50% at the concentration of 0....