BACKGROUND Mutations in the TRPC6 gene have been reported in six families with adult-onset (17-57 years) autosomal dominant focal segmental glomerulosclerosis (FSGS). Electrophysiology studies confirmed augmented calcium influx only in three of these six TRPC6 mutations. To date, the role of TRPC6 in childhood and adulthood non-familial forms is unknown. METHODS TRPC6 mutation analysis was pe...

abstract objective: to investigate the anesthesia-postoperative awakening time (at) of hepatitis- related cirrhosis patients and their relations to grading scores, portal venous pressure (pvp), prealbumin (pa), and age, to predict postoperative at and provide a basis for adjustment of anesthetic doses during operation. methods: atotal of 71 patients with hepatic cirrhosis and hypersplenism at a...

in this paper data were collected from 120 farmers in north khorassan province for the two periods (2005-2007) in order to survey the role of rain-fed lentil risk profile for designing an insurance model. to evaluate looses of each risk, risk frequency, risk impact criteria’s as well as risk matrix were used. results showed that low risk was the largest risk area. during study period, a decreas...

BACKGROUND In Fabry nephropathy, alpha-galactosidase deficiency leads to accumulation of glycosphingolipids in all kidney cell types, proteinuria and progressive loss of kidney function. METHODS An international working group of nephrologists from 11 Fabry centres identified adult Fabry patients, and pathologists scored histologic changes on renal biopsies. A standardized scoring system was d...

BACKGROUND Tumor characteristics affect surgical complexity and outcomes of partial nephrectomy (PN). OBJECTIVE To develop an Arterial Based Complexity (ABC) scoring system to predict morbidity of PN. DESIGN, SETTING, AND PARTICIPANTS Four readers independently scored contrast-enhanced computed tomography images of 179 patients who underwent PN. INTERVENTION Renal cortical masses were cat...

conclusions stability of the clavicle is crucial for shoulder function and care should be taken not to miss or underestimate segmental bipolar fractures even with a low energy mechanism. authors believe that operative treatment should be taken into consideration for displaced fractures. introduction clavicle fractures are very common, accounting for approximately 4% of all adult fractures. segm...

Traditional statistical speech recognition systems typically make strong assumptions about the independence of observation frames and generally do not make use of segmental information. In contrast, when the segmentation is known, existing classifiers can readily accommodate segmental information in the decision process. We describe an approach to connected word recognition that allows the use ...

We welcome the interest shown by colleagues in Rome about the Ulcerative Colitis Endoscopic Index of Severity [UCEIS]1,2 and their suggestion that it might be enhanced by segmental scoring at full colonoscopy. When the score was being developed,3 the international working group felt that a major goal was for the score to be simple, not to replicate the relative complexity of endoscopic scoring ...

the bender-gestalt test was given to thirty mentally-retarded psychiatric patients. the mean, standard deviation, and standard error were 56.73, 26.25, and 4.80 respectively. rotation was the most frequent major deviation which occurred in all the designs. design # 7 was the most difficult one to be reproduced in the sample. this design by itself, was subject to 47% of distortion, 79% of omissi...