The extensive distribution and simultaneous termination of seizures across cortical areas has led to the hypothesis that seizures are caused by large-scale coordinated networks spanning these areas. This view, however, is difficult to reconcile with most proposed mechanisms of seizure spread and termination, which operate on a cellular scale. We hypothesize that seizures evolve into self-organi...

We consider as a mathematical model of human cortical electrical activity a system of fourteen ordinary differential equations. With appropriate parameters, the model produces activity characteristic of a seizure. To prevent such seizures, we incorporate feedback controllers into the model dynamics. We show that three controllers--a linear feedback controller, a differential controller, and a f...

The purpose of this study is to analyze how dynamic capabilities are integrated into open innovation support firms pursuing innovation. Dynamic enable adjust emerging changes through redesigning resource configuration. Nevertheless, for obtaining external knowledge and resources has not been observed in previous studies. Utilizing seven small medium enterprises (SMEs) with various degrees techn...

Transient loss of consciousness associated with focal temporal lobe seizures is a complex phenomenon with life-threatening repercussions. In this issue of Neuron, Motelow et al. (2015) describe decreased cholinergic drive and suppressed subcortical arousal in seizures as a novel mechanism for impaired cortical function.

This paper examines the development of web aggregators, entities that collect information from a wide range of sources, with or without prior arrangements, and add value through post-aggregation services. New Web-page extraction tools, context sensitive mediators, and agent technologies have greatly reduced the barriers to constructing aggregators. We predict that aggregators will soon emerge i...