reduced sperm quantity and motility are primary causes of infertility in men. before researchers showed that, nsun7 gene has roles in sperm motility of mouse, that creation defect in this gene is cause infertility. this gene in human located in chromosome 4, with 12 exons and a hot spot exon (exon7). our aim is study of the mutations of the exon7 in the normospermic and asthenoteratospermic men...

BACKGROUND Carlsen and coworkers (1992) reviewed 61 heterogeneous observational studies on semen quality published between 1938 and 1990. This review indicates that mean sperm density decreased significantly between 1940 and 1990. An extended meta-analysis with 101 studies confirmed a decline in sperm density for the period from 1934 to 1996 (2000). The key message of the meta-analyses is that ...

PURPOSE The aim of this study was to evaluate the relationship of seminal parameters with the neutrophil-to-lymphocyte ratio (NLR) and the platelet-to-lymphocyte ratio (PLR), which are inflammatory markers, in men with an abnormal semen analysis and men with normozoospermia. MATERIALS AND METHODS Fifty-seven men with abnormal semen analyses and 59 men with normozoospermia were included in thi...

In 1996-1998, the authors measured prostate-specific antigen (PSA) in vaginal fluid to assess the frequency of female condom failure and to evaluate the association of self-reported failure with semen exposure. Women at low risk of sexually transmitted diseases (n = 210) were recruited in Birmingham, Alabama. They were trained to use the female condom, sample vaginal fluid before and after cond...

BACKGROUND Standardization of the semen analysis may improve reproducibility. We assessed variability between laboratories in semen analyses and evaluated whether a transformation using Z scores and regression statistics was able to reduce this variability. MATERIALS AND METHODS We performed a retrospective cohort study. We calculated between-laboratory coefficients of variation (CVB) for spe...

In this study we have described our varicocele cases in terms of associated symptoms/signs. In addition, we have tested the correlation between semen parameters and varicocele grades and compared the relative frequencies of associated symptoms/signs in different varicocele grades. 1 19 referred cases of varicocele were categorized based on clinical criteria into 3 grades by one examiner. T...

Background Leukocytes linked directly and indirectly to reactive oxygen species (ROS) formation. Although leukocytospermia is defined as the presence of ≥1×106 white blood cells/mL (WBC/mL) in a semen sample, the presence of less than 1×106 WBC/mL (low-level leukocytospermia) still can produce a detectable amount of ROS, impairing sperm function and lowering the chances of pregnancy. Low concen...

INTRODUCTION Studies that compare the impact of different infectious entities of the male reproductive tract (MRT) on the male accessory gland function are controversial. MATERIALS AND METHODS Semen analyses of 71 patients with proven infections of the MRT were compared with the results of 40 healthy non-infected volunteers. Patients were divided into 3 groups according to their diagnosis: ch...

PURPOSE We calculated the compliance rate and determined which population of men would be more or less likely to be compliant with semen analysis followup based on demographic information and complication rates. MATERIALS AND METHODS We retrospectively reviewed the records of 946 consecutive patients who underwent vasectomy at an ambulatory clinic, as performed by 1 urologist. Standard follow...

background: sperm selection is generally used to describe methods for separation of spermatozoa for in-vitro-assisted reproduction. few studies reported relation in vivo fertility and semen parameters after selection of fertile spermatozoa; hence, our research attempt to assess different semen parameters after post-thaw (pt) or after selecting sperm sample (ssp), using density gradient separati...