Doxorubicin (DXR) is one of the most effective antineoplastic agents, but its use is limited by its myocardial toxicity. Myocardial injury reduces the cyclic variation of integrated backscatter (CV-IBS) and so the present study was designed to investigate whether CV-IBS can be used to detect the early phase of myocardial damage in patients receiving DXR. Thirty-four subjects constituted the stu...

Transport of calcium (Ca) and cadmium (Cd) was examined along the gastro-intestinal tract (GIT) of freshwater and seawater Oncorhynchus mykiss irideus (FWT and SWTies respectively) using in vitro and in vivo experiments. Based on known physiological differences between FWT and SWT which aid in regulating ion levels and osmolarity, we hypothesized that SWT would have lower rates of Ca uptake. Al...

Abstract Background/Introduction Cardiac magnetic resonance imaging (CMR) is regarded as the reference method in assessing left ventricular (LV) myocardial mass. However, 2-dimensional echocardiography (Echo) still used due to availability and practicability. Purpose We sought assess measurements of LV mass from Echo exams validate results with CMR on a large cohort patients. Methods analyzed 3...

We sought to test the effectiveness of the ECG as a measure of increased left ventricular wall mass in children with high blood pressure. One hundred eighty-one children, ages 9-18 years, were selected from the lowest, middle and highest quintile of systolic blood pressure from the Muscatine Study, based upon two biennial school screenings. After correction for age, sex, height, weight and skin...

BACKGROUND We aimed to study left ventricular (LV) geometry assessed by length (LVWL), external diameter (LVEDD) and relative wall thickness (RWT) in relation to age, body size and gender in healthy individuals. METHODS 1266 individuals underwent echocardiography in the Nord-Trøndelag Health Study (HUNT3), Norway. Septum thickness (IVS), posterior wall thickness (LVPWd) and end-diastolic inte...

S egmental variation in left ventricular (LV) wall thickness is important in characterizing hypertrophic cardiomyopathy, post-infarction remodeling, and myocardial noncompaction. In each of these disorders, cardiac magnetic resonance (CMR) has greatly extended our understanding due to its ability to comprehensively assess LV structure, function, and myocardial composition over the entire LV cha...

BACKGROUND Cycle-dependent variation of myocardial integrated backscatter (CV-IB) is an objective measurement that may detect myocardial abnormalities. However, no data exist about the prognostic value of CV-IB in primary cardiac amyloidosis. METHODS AND RESULTS We prospectively examined 208 consecutive biopsy-proven patients with primary amyloidosis. The magnitude of CV-IB was analyzed at th...

AIM We sought to assess the reliability of some basic echocardiographic data obtained by trained sonographers using a hand-held ultrasound device. METHODS One hundred and twelve consecutive patients (mean age 61, 64 males) referred for in-hospital or ambulatory routine echocardiography were considered. All patients underwent two-dimensional and colour Doppler examination performed by a traine...

Twent~-two patients with atrial septal defect (ostium secundum type and amua venosus) were studied by echucardiography before and after surgery. The sizes of the various heart chambers right and left ventricles, Ieft atrium and aortic root and the interventricular seprum and the left ventricular posterior free wall (motion and thickness) were analvsed and compared in the pre and postoperative p...