Chaperone-assisted selective autophagy (CASA) is a tension-induced degradation pathway essential for muscle maintenance. Impairment of CASA causes childhood muscle dystrophy and cardiomyopathy. However, the importance of CASA for muscle function in healthy individuals has remained elusive so far. Here we describe the impact of strength training on CASA in a group of healthy and moderately train...

Fleury Diagnostic Center, Section of Radiology, São Paulo SP, Brazil; Santa Casa de Misericórdia de São Paulo, Section of Radiology, São Paulo SP Brazil; Santa Casa de Misericórdia de São Paulo, Section of Neurology, São Paulo SP, Brazil; Santa Casa de Misericórdia de São Paulo, Section of Neurosurgery, São Paulo SP, Brazil; Santa Casa de Misericórdia de São Paulo, Section of Pathology, São Pau...

One of the goals of the National Science Foundation Engineering Research Center (ERC) for Collaborative Adaptive Sensing of the Atmosphere (CASA) is to improve storm-scale numerical weather prediction (NWP) by collecting data with a dense X-band radar network that provides high-resolution low-level coverage, and by assimilating such data into NWP models. During the first spring storm season aft...

Exposure at the working place to various substances, that may affect semen quality is possible and should be investigated in detail. One appropriate method for this is computer-assisted sperm analysis (CASA) which offers multiple benefits in comparison to manual evaluation. However, several pitfalls exist, which make the evaluation of data obtained from CASA difficult to interpret. In the prese...

Accurate determination of sperm concentration in fluid suspension is a critical component in a semen analysis. Inaccurate estimations can lead to misinterpretation of the spermiogram and, in the case of livestock production, can lead to faulty insemination doses, which can adversely affect stud power, fertility, fecundity, and cost effectiveness of breeding programs. Capillary-loaded slides, li...

Selective Sequential Extractions (SSE) were used to study the retention mechanisms of heavy metals on three estuarine alluvium soil columns obtained from leaching experiment for up to 5 pore volumes (PV). Leaching results indicate that almost 99 % of heavy metals (Pb, Cu, and Zn) were retained in the soils with the Ce/Co values in the order of 10 -3 to 10. This is in accord with the results obt...

Separating voiced speech from its mixtures with interferences in monaural condition is not only an important but also challenging task. As multipitch tracking can enable much better performance of speech separation for CASA systems, we propose a new multipitch determination algorithm, which can be used under various kinds of noise conditions. In the process of multipitch estimation, a new repre...

1 Assistant Physician, Dermatology Clinic, Santa Casa de Misericórdia de São Paulo – São Paulo (SP), Brazil 2 PhD; Professor, Università Degli Studi Di Modena e Reggio Emilia – Modena, Italy 3 Dermatology Specialist, Santa Casa de Misericórdia de São Paulo 4 Assistant Physician, Anatomical Pathology Department, Santa Casa de Misericórdia de São Paulo 5 PhD; Adjunct Head of Dermatology, Santa Ca...

Sixteen USEPA priority polycyclic aromatic hydrocarbons (PAHs) extracted by Soxhlet extraction (S-PAHs) with dichloromethane and routine accelerated solvent extraction (A-PAHs) with 1:1 toluene/methanol, respectively, were investigated in 24 soil samples from two cities in the center of the Pearl River Delta, South China. Polycyclic aromatic hydrocarbons, methylphenanthrene and perylene, in two...

The knowledge of the application behavior allows predicting the application workload during its execution and forecasting distributed data accesses. In order to obtain such data, different strategies can be employed, varying from simple source code analysis, sequential access pattern extraction (Kotz & Ellis, 1993), history-based approaches (Gibbons, 1997; Smith, Foster & Taylor, 1998) and on-l...