BACKGROUND Severe dehydration is generally believed to be a cause of significant hyperbilirubinemia in newborn babies. This study aimed to analyze the weight loss of healthy term newborn infants at 24, 48 and 72 hours after birth to predict significant hyperbilirubinemia at 72 hours. METHODS From January 2007 to December 2008, we conducted this retrospective chart review by measuring total bi...

BACKGROUND Hyperbilirubinemia is a frequently seen condition in neonates. This study was undertaken to determine the role of urinary tract infections (UTIs) in the etiology of indirect hyperbilirubinemia in neonates with jaundice in their first two weeks of life. METHODS The study was conducted prospectively. The subjects were neonates aged 4-14 days with hyperbilirubinemia which could not be...

A number of genetic risk factors have been implicated in the development of neonatal severe hyperbilirubinaemia. This includes mutations in the uridine glucoronosyl transferase 1A1 (UGT1A1) gene which is responsible for unconjugated hyperbilirubinemia in Gilbert's Syndrome. We studied the prevalence of UGT1A1 gene mutations in a group of Malay neonates to determine whether they are risk factors...

Background: Neonatal hyperbilirubinemia occurs in about 60% of newborns. If not managed properly, it can progress to severe neonatal hyperbilirubinemia (SNNJ) leading to death or permanent disability. Aim: To assess nurse's knowledge and practice about neonate with hyperbilirubinemia. Subjects: 41 nurses working in nine districts hospital in Minia governorate each district one hospital and from...

Severe hyperbilirubinemia in a pregnant mother suffering from Crigler-Najjar syndrome type II is a threat to the unborn child and may result in brain injury. We report the case of a Gly71-->Arg/Tyr486-->Asp homozygous mother of East Asian descent, who was treated with phototherapy during embryogenesis and with phenobarbital during the rest of the pregnancy. This resulted in significantly reduce...

methods this prospective observational study was conducted in a tertiary level neonatal intensive care unit, princess esra hospital, deccan college of medical sciences, hyderabad, telangana, india. consecutive intramural and extramural neonates admitted to neonatal intensive care unit with the rh-negative mother’s blood group and hyperbilirubinemia were enrolled. neonates born to rh+ve mothers ...

Hyperbilirubinemia, caused by the accumulation of unconjugated bilirubin, is one of the most common clinical diagnoses in both premature and term newborns. Owing to the fact that bilirubin is metabolized solely through glucuronidation by UDP-glucuronosyltransferase (UGT) 1A1, it is now known that immaturity of UGT1A1, in combination with the overproduction of bilirubin during the developmental ...

background and aims: this is a pilot study investigated the prevalence of hearing impairment and the impact of the known risk factors for hearing loss on infants at risk born in kuwait. methods: two hundred infants with risk of hearing impairment who met the joint committee on infants hearing (1990) criteria were screened. all newborns were included in this study if they had hospital stay for m...