Transsexualism is not usually indicative of psychopathology. In carefully selected individuals, with multidisciplinary support, a change of social gender role and cross-sex hormone treatment greatly improves the psychological and social state. Sustained improvement merits gender reassignment surgery. The key is early referral with subsequent primary care cooperation in the treatment plan.

BACKGROUND Gender identity disorder is a rare entity in psychiatry which affects deep instincts and personal identity. A review of the recent literature has shown that research of socio-demographic characteristics of transsexual patients is sporadic. There are very few investigations which consider the socio-demographic characteristics in individuals with disharmonized sex and gender identity. ...

This special issue represents a comprehensive, multidisciplinary look on gender dysphoria. We invited investigators to contribute original research articles as well as review articles that will further encourage the continuing efforts to understand the role of gender dysphoria, sex reassignment surgery, modalities of surgical treatment, and the patient's evaluation of hormonal, psychosocial, an...

BACKGROUND Gender identity disorder (GID) is a distressing disorder characterized by a persistent unhappiness with one's own sex and a desire to be of the opposite sex as well as seeking sex reassignment surgery for the same. The aim of the study was to assess the Minnesota Multiphasic Personality Inventory-2 (MMPI-2) profiles in patients with GID and examine differences in the profiles based o...