Here we report a novel approach for preparation of a 6-day transdermal drug delivery system (TDDS) as treatment for mild to moderate Alzheimer’s disease. The spray drying method was used to prepare microparticles containing the anti-Alzheimer drug. The content of the drug was determined by High Performance Liquid Chromatography (HPLC) method. The morphology and size range of the microparticles ...

the support vector machine (svm) is a relatively new machine learning method which is increasingly being applied to engineering problems and have yielded encouraging results. because of complex behavior of elastoplastic of web panels of plate girders under patch loading, almost none of the proposed methods provides consistent and accurate predictions of patch load capacity. consequently, altern...

background: cutaneous manifestations are commonly observed in the neonatal period. it is important to differentiate physiologic skin lesions from pathologic ones to avoid parents’ concerns. regarding this, the current study aimed to investigate the frequency and localization of salmon patch (sp) and mongolian spot (ms) in iranian newborns to assess the potential relationship between the neonata...

The first tetrapod fossil from the Rewan Formation of the Galilee Basin, central Queensland, Australia, is identified as Lydekkerina huxleyi, a stereospondyl found elsewhere only in the Lystrosaurus Assemblage Zone of South Africa. Apomorphies shared with L. huxleyi are: anterior palatal vacuity with anterodorsal projections from its posterior margin; ventral surface of skull roof with series o...

A new tree frog species of the genus Scinax from the interfluve between the Purus and Madeira rivers, Brazilian Amazonia, is described and illustrated. The new species is diagnosed by medium body size, snout truncate in dorsal view, ulnar and tarsal tubercles absent, nuptial pads poorly developed, skin on dorsum shagreen, dorsum light brown with dark brown spots and markings, white groin with b...

Here we report a novel approach for preparation of a 6-day transdermal drug delivery system (TDDS) as treatment for mild to moderate Alzheimer’s disease. The spray drying method was used to prepare microparticles containing the anti-Alzheimer drug. The content of the drug was determined by High Performance Liquid Chromatography (HPLC) method. The morphology and size range of the microparticles ...

the dynamic response of a transversely isotropic, linearly elastic layer bonded to the surface of a half-space of a different transversely isotropic material under arbitrary shape surface loads is considered. with the help of displacements and stresses green’s functions, an analytical formulation is presented for the determination of the displacements and stresses at any point in both surface l...

abstract competition is a phenomenon that influences the size, structure and stability of insect communities, particularly on solitary endoparasitoids species. although, competition normally incurs costs, it might be adaptive for the surviving individual. to determine which factors affect the patch use strategy of foragers under competition, the effect of previous experience with hosts already-...

An equivalent circuit model for predicting the frequency response of a square ring slot frequency selective surface (SRS-FSS) for normal incidence is described. The proposed FSS consists of an array of square patches centered within a wire grid. The presented circuit model is formed by the impedance of the wire grid that is parallel with the impedance of the patch array, also the mutual couplin...