نتایج جستجو برای: sicam 1

تعداد نتایج: 2752593  

Journal: :Clinical chemistry 2008
Mahyar Khaleghi Zeenat Ali Thomas H Mosley Stephen T Turner Iftikhar J Kullo

BACKGROUND Higher plasma concentrations of soluble adhesion molecules have been shown to be associated with increased risk of cardiovascular events. We investigated the association of soluble intercellular adhesion molecule-1 (sICAM-1) and soluble vascular cell adhesion molecule-1 (sVCAM-1) with ankle-brachial index (ABI), a measure of peripheral arterial disease (PAD), in a biethnic cohort of ...

Journal: :Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2006
Mohamed E Suliman A Rashid Qureshi Olof Heimbürger Bengt Lindholm Peter Stenvinkel

BACKGROUND Inflammation is thought to contribute to initiation and aggravation of atherosclerosis through a process predominantly mediated by adhesion molecules. The aims of this study were to investigate the association between the concentrations of circulating soluble intercellular (sICAM-1) and vascular cellular (sVCAM-1) adhesion molecules and clinical outcome, and to evaluate the effect of...

Journal: :BMC Cardiovascular Disorders 2007
Weihong Tang James S Pankow J Jeffrey Carr Russell P Tracy Suzette J Bielinski Kari E North Paul N Hopkins Aldi T Kraja Donna K Arnett

BACKGROUND Data accumulated from mouse studies and in vitro studies of human arteries support the notion that soluble intercellular adhesion molecule-1 (sICAM-1) and monocyte chemoattractant protein-1 (MCP-1) play important roles in the inflammation process involved in atherosclerosis. However, at the population level, the utility of sICAM-1 and MCP-1 as biomarkers for subclinical atheroscleros...

Journal: :Circulation 2003
Kenneth K Wu Nena Aleksic Christie M Ballantyne Chul Ahn Harinder Juneja Eric Boerwinkle

BACKGROUND Results from previous ARIC (Atherosclerosis Risk In Communities) analyses indicate that soluble intercellular adhesive molecule-1 (sICAM) and soluble thrombomodulin (sTM) levels are associated with risk of coronary heart disease (CHD) in an opposite direction. A high sICAM level increases the risk of CHD, whereas a high level of sTM has a lower risk of CHD. It was unclear whether the...

Journal: :European journal of clinical investigation 2002
A Becker V W M van Hinsbergh A Jager P J Kostense J M Dekker G Nijpels R J Heine L M Bouter C D A Stehouwer

Increased plasma levels of soluble adhesion molecules are associated with an increased risk of atherothrombosis. The pathophysiological mechanisms responsible for these associations are not known. The aim of the present study was to investigate the association of soluble intercellular adhesion molecule-1 (sICAM-1) concentration and risk of cardiovascular and all-cause mortality among individual...

2013
Sahar E. El-Deek Hoda A. Makhlouf Tahia H. Saleem Manal A. Mandour Nahed A. Mohamed

OBJECTIVE The aim of this study was to estimate the serum levels of surfactant protein D (SP-D), soluble intercellular adhesion molecule-1 (sICAM-1), and high-sensitivity C-reactive protein (hs-CRP) in patients with chronic obstructive pulmonary disease (COPD) and to assess the correlation of these indices with COPD severity. SUBJECTS AND METHODS This analytic cross-sectional study was carrie...

Journal: :Journal of neurotrauma 1998
U E Pleines J F Stover T Kossmann O Trentz M C Morganti-Kossmann

The intercellular adhesion molecule-1 (ICAM-1) expressed by endothelial cells is crucial in promoting adhesion and transmigration of circulating leukocytes across the blood-brain barrier (BBB). Migrated immunocompetent cells, in turn, release mediators that stimulate glial and endothelial cells to express ICAM-1 and release cytokines, possibly sustaining cerebral damage. Following activation, p...

Journal: :International Archives of Allergy and Immunology 2013

Journal: :PLoS Genetics 2008
Guillaume Paré Daniel I. Chasman Mark Kellogg Robert Y. L. Zee Nader Rifai Sunita Badola Joseph P. Miletich Paul M. Ridker

While circulating levels of soluble Intercellular Adhesion Molecule 1 (sICAM-1) have been associated with diverse conditions including myocardial infarction, stroke, malaria, and diabetes, comprehensive analysis of the common genetic determinants of sICAM-1 is not available. In a genome-wide association study conducted among 6,578 participants in the Women's Genome Health Study, we find that th...

Journal: :Human reproduction 1998
E Daraï A F Bringuier F Walker-Combrouze G Feldmann P Madelenat J Y Scoazec

The potential of the soluble forms of the adhesion molecules ICAM-1 (sICAM-1), CD44std (sCD44std) and E-cadherin (sE-cadherin) was tested for the diagnosis of benign and malignant cystic epithelial tumours of the ovary. Concentrations of sICAM-1, sCD44 std and sE-cadherin were measured by enzyme-linked immunosorbent assay (ELISA) in the serum and cyst fluid obtained from 23 patients with luteal...

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