Some peptides that are highly conserved between insects and mammals have anti-tumor action. Screening for inhibitors of cell growth from animal fluids may provide useful clues to anti-tumor drugs. Inducers of autophagy also have anti-tumor activity. The current authors recently studied a protein found in silkworm hemolymph, Niemann-Pick disease type C2 (NPC2). This protein, which is highly cons...

The silkworm Bombyx mori is an economically important species. White muscardine caused by Beauveria bassiana is the main fungal disease in sericulture, and understanding the silkworm responses to B. bassiana infection is of particular interest. Herein, we investigated the molecular mechanisms underlying these responses in two silkworm strains Haoyue (HY, sensitive to B. bassiana) and Kang 8 (K8...

oral supplementation with potassium bromide (10, 20 and 40 ?g/ml) to fifth instar larvae of csr2, csr4 and csr2xcsr4 crossbreed races of the silkworm, bombyx mori resulted in a significant increase in the fat body glycogen in all the treated groups and in all the three races of the silkworm, b. mori. the fat body protein content was increased with 20 and 40 ?g/ml treated groups in csr2 and csr4...

The wild silkworm Bombyx mandarina is widely believed to be an ancestor of the domesticated silkworm, Bombyx mori. Silkworms are often used as a model for studying the mechanism of species domestication. Here, we performed transcriptome sequencing of the wild silkworm using an Illumina HiSeq2000 platform. We produced 100,004,078 high-quality reads and assembled them into 50,773 contigs with an ...

The genetic variation and diversity among fifty-eight polyvoltine silkworm genotypes was estimated by using ten economic traits. The results revealed that the single shell weight showed higher genetic variation such as PCV% (17.20%), GCV% (12.93%), and heritability (56.5%) followed by single cocoon weight, shell ratio and matured larval weight. The D2 (Mahalonobis? distance) statistics reveal...

An attempt was made to rear the eri silkworm, Philosamia ricini on leaves of caster and reared under laboratory condition. It observed that is a primary potential host silkworm. The growth parameters cocoon characters silkworm were normal. successfully lasted its life cycle ranged from 38 40 days. effective rate rearing, weight pre-spinning larvae, cocoon, shell pupae 70 75 per cent, 6 7 g, 3.0...

Silkworm (Bombyx mori) is a species of agricultural importance, as well as a model organism for Lepidoptera insects. Proteomic method has been widely used in silkworm research, and a robust mass spectrometry-compatible protein extraction method is urgently needed. In this study, we adapted phenol extraction method to extract silkworm midgut protein, and coupled this method with pH 5 8 gel strip...

Active peptide from shark liver (APSL) is a cytokine from Chiloscyllium plagiosum that can stimulate liver regeneration and protects the pancreas. To study the effect of orally administered recombinant APSL (rAPSL) on an animal model of type 2 diabetes mellitus, the APSL gene was cloned, and APSL was expressed in Bombyx mori N cells (BmN cells), silkworm larvae and silkworm pupae using the silk...

the domesticated silkworm, bombyx mori linn., a lepidopteran molecular model and an important economic insect that are emerging as an ideal molecular genetic resource for solving a broad range of biological problems. the silkworm, b. mori produces massive amount of silk proteins during the final stage of larval development. these proteins are stored in the middle silk gland and they are dischar...