The DNA-damaging activities of organic rubber additives such as rubber vulcanizing agents, vulcanization accelerators and rubber anti-oxidants were investigated by the rec-assay using spores of Bacillus subtilis strains H 17 and M 45. For metabolic activation, 9,000 X g supernatant solutions of the liver homogenate of Sprague-Dawley male rats previously treated with aroclor 1,254 were used. Spo...

The use of2H2O in estimating gluconeogenesis' contribution to glucose production (%GNG) was examined during progressive fasting in three groups of healthy subjects. One group ( n = 3) ingested2H2O to a body water enrichment of ≈0.35% 5 h into the fast. %GNG was determined at 2-h intervals from the ratio of the enrichments of the hydrogens at C-5 and C-2 of blood glucose, assayed in hexamethylen...

The researches of Ehrlich and his coworkers during the past decade, which led to the discovery of salvarsan, have created a new procedure in the search for remedies for the control of infectious diseases. The discovery of this drug was the result of a logically conducted development of the chemistry of organic arsenic compounds in the directions indicated by their biological properties. This ne...

Low-temperature aqueous chemical growth methods have shown great potential in the synthesis of ZnO nanostructures. Hexamethylenetetramine (HMTA) is the most common chemical substance used in the hydrothermal synthesis. In this study zinc oxide nanoparticles were prepared via hydrothermal growth using zinc acetate dihydrate and sodium hydroxide, as precursors instead of HMTA, as it is commercial...

The Cover Feature shows a combination that could be called the ugly duckling of Ugi 4-component reactions, which involves concomitant use ammonia/formaldehyde pair. There was not single methodology so far to successfully achieve this goal. metamorphosis finally happen with intermediacy hexamethylenetetramine (HMTA), allows in situ generation both ammonia and formaldehyde for reactions carboxyli...