the paranasal sinuses are known to be a rare location for metastasis. renal cell carcinoma (rcc) is the most frequent primary tumor to metastasize to the sinonasal region, followed by lung and breast cancer. in particular, clear cell type rcc, which represents approximately 85% of rccs, is characterized by early metastasis, and it sometimes spreads to unusual sites (1, 2). metastatic tumors in ...

extramedullary plasmacytoma is a rare neoplasm characterized by monoclonal proliferation of plasma cells. most lesions occur in the head and neck, primarily in the upper aerodigestive tract. the nasal cavity and nasal septum are the most common sites of occurrence. in this report, three patients admitted in our clinic with history of nasal obstruction and/or epistaxis. patients were diagnosed w...

The sinonasal cavities are rare locations for metastases. Metastases to these locations are usually solitary and produce similar symptoms to those of a primary sinonasal tumor. Nasal obstruction and epistaxis are the most frequent symptoms. The maxillary sinus is most frequently involved. The most common primary tumor sites to spread to this region originate in the kidney, breast, thyroid, and ...

PURPOSE OF REVIEW Sinonasal undifferentiated carcinoma is a rare and extremely malignant tumor of the paranasal sinuses. Historically, treatment outcomes have been poor. This review presents recent data on the management of sinonasal undifferentiated carcinoma and examines treatment trends that may result in improved locoregional control and survival. RECENT FINDINGS Patients who receive aggr...

BACKGROUND Sinonasal squamous cell carcinomas (SCCs) are rare tumors with no etiologic link to tobacco and alcohol, as opposed to other SCCs of the head and neck (HNSCC). Little is known about the genetic changes in sinonasal SCC. METHODS DNA copy number changes of sinonasal SCC were analyzed by multiplex ligation-dependent probe amplification (MLPA) and microarray comparative genomic hybridi...

Background Transcytosis of immunoglobulin A (IgA) through polarized bronchial and sinonasal epithelial cells is mediated by the polymeric immunoglobulin receptor (pIgR), which represents the rate-limiting factor for this frontline protective mechanism in the airways. pIgR expression is decreased in COPD, lung cancer and nasopharyngeal carcinoma, while its role in sinonasal chronic inflammatory ...

Changes in imaging sinonasal inflammatory disease have paralleled changes in the treatment of chronic sinusitis. As functional endoscopic sinus surgery has become a more widespread technique, coronal computed tomography (CT) has become the primary imaging modality, replacing plain radiography. Knowledge of the plethora of sinonasal anatomic variations and the inherent surgical implications is c...

Sinonasal foreign bodies are rare clinical entities. Their presence in the sinuses can originate complications, so their removal is always indicated. We present 3 cases of sinonasal foreign body, indicating their symptoms, imaging findings and surgical removal. Each patient was assessed with computerized tomography of the sinuses, rigid endoscopy, and then surgical removal. We confirmed the pre...

Sinonasal melanoma is a rare disease with limited data regarding its optimal treatment. It is an aggressive disease with up to 60% of patients developing local recurrence or distant metastases in the first 24 months after treatment. We report a case of sinonasal melanoma involving the skull base which was treated by endoscopic anterior craniofacial resection together with brachytherapy postoper...