.............................................................................................................................. 4 INTRODUCTION ...................................................................................................................... 6 Energy metabolism in skeletal muscle ................................................................................... 6 Dynamics of...

Skeletal muscle contains multiple cell types that work together to maintain tissue homeostasis. Among these, satellite cells (SC) and fibroadipogenic progenitors (FAPs) are the two main stem pools. Studies of these using animal models have shown importance interactions between in repair healthy muscle, degeneration dystrophic muscle. Due unavailability fresh patient biopsies, similar analysis h...

A three-dimensional human neuromuscular tissue model that mimics the physically separated structures of motor neurons and skeletal muscle fibers is presented.

Skeletal muscle is a vital tissue not only for maintaining posture and body movements but also energy metabolism in human body. highly plastic response to various stimuli, resistance exercise or anabolic hormones can increase mass, which termed “muscle hypertrophy”. Contrary, immobility, aging severe illness reduce atrophy”. Loss of skeletal mass associated with loss independent living, the mor...

Skeletal muscle mass, quality and adaptability are fundamental in promoting muscle performance, maintaining metabolic function and supporting longevity and healthspan. Skeletal muscle is programmable and can 'remember' early-life metabolic stimuli affecting its function in adult life. In this review, the authors pose the question as to whether skeletal muscle has an 'epi'-memory? Following an i...