conclusions findings of this study showed that integron can have a limited frequency in s. aureus isolated from clinical sample in tehran. results among the 200 samples, 1% of the strains (two isolates) contained the class 1 integron gene. the results of this study showed that the highest frequency of the obtained samples belonged to males and the isolates occurred mostly in individuals aged 51...

It is a truism that almost any drug can produce any sort of reaction, and in the diagnosis of all types of skin eruption drug reactions either allergic or otherwise must be considered. As has been repeatedly emphasized drug eruptions have now replaced syphilis as the great mimic. The clinical aspect of drug reactions is such a vast topic that I wish to narrow it down to those reactions which si...

Adverse drug reactions are a common clinical problem. It has been estimated that 6% to 15% of hospitalized patients experience some sort of adverse drug reaction. Clinical manifestations of adverse drug reactions include skin rash; a serum sickness-like reaction; drug fever; pulmonary, hepatic, and renal involvement; and systemic anaphylaxis. Many of these adverse events are not immunologically...

Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe cutaneous adverse drug reaction, which mainly caused by drugs; these usually associated with high degree of morbidity mortality. They characterized mucocutaneous tenderness typically haemorrhagic erosions, erythema more or less detachment as blisters areas denuded skin. High risk drugs for the development SJS-TEN inc...

Three patients with sensitivity to an intravenous anaesthetic-thiopentone, propanidid, and Althesin (alphadolone and alphaxalone)-are described. In the cases of thiopentone and Althesin the reaction was characterized by cardiovascular collapse, while bronchospasm also occurred with thiopentone. The reaction to propanidid was a direct skin sensitivity. All patients had a personal or family histo...

background: nosocomial infections are one of the most important medical problems in developed and under developing countries which cause the spread of infections diseases in society. pseudomonas aeroginosa is one of the most important causes of hospital infections, especially in wounds from operated patients. increase in antibiotic-resistance of pseudomonas aeroginosa cause a lot of problems fo...

Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a rare but potentially life-threatening hypersensitivity reaction characterized by widespread erythematous skin eruptions with fever, lymphadenopathy and visceral involvement-hepatitis, nephritis, pericarditis, and pneumonitis. There are numerous reports describing the management of such patients in intensive care units b...

Skin testing has been utilised to determine the culprit allergenic agent in drug reactions. Its application in the setting of hypersensitivity reaction relating to combination chemotherapeutic regimens may help identify the causative drug, allowing drug that is safe to be continued and avoiding limiting treatment options for patients. We report what we believe to be the first published case of ...

Hong Kong Med J ⎥ Volume 20 Number 5 ⎥ October 2014 ⎥ www.hkmj.org An 86-year-old man presented with leukocytosis in December 2009. Bone marrow biopsy showed chronic myeloid leukaemia in chronic phase and cytogenetic studies showed t(9;22)(q34;q11.2) translocation. He was initially put on imatinib 300 mg daily; subsequently, this was increased to 400 mg daily. He developed pruritic skin rash wi...

Drug eruptions are among the most common adverse drug reactions, affecting approximately 3% of hospitalized patients. A fixed drug eruption (FDE) is a distinct drug-induced reaction pattern that characteristically recurs at the same skin or mucosal site. We report a case of a 2-year-old girl with bullous FDE due to Tachipirina syrup, a preparation containing paracetamol, a commonly used nonster...