PURPOSE Fiber carbon is the most common material used in treating couch as it causes less beam attenuation than other materials. Beam attenuation replaces build-up region, reduces skin-sparing effect and causes target volume under dosage. In this study, we aimed to evaluate beam attenuation and variation of build-up region in 550 TxT radiotherapy couch. MATERIALS AND METHODS In this study, we...

Compact and cost-effective systems for in vivo fluorescence and near-infrared imaging in combination with activatable reporters embedded inside the skin to sample interstitial fluid or blood can enable a variety of biomedical applications. However, the strong autofluorescence of human skin creates an obstacle for fluorescence-based sensing. Here we introduce a method for quantitative fluorescen...

PURPOSE To develop a realistic yet flexible 4D digital phantom based on patient anatomy for dynamic estimation of organ doses due to external ionizing radiation. METHODS In this work, we propose to build a 4D digital phantom based on patient CT anatomy and time-tagged CT information. A regional 4D-CT is first acquired on the patient around lesion with a RPM system. By binning CT information a...

PURPOSE In recent times, longitudinal field MRI-linac systems have been proposed for 6 MV MRI-guided radiotherapy (MRIgRT). The magnetic field is parallel with the beam axis and so will alter the transport properties of any electron contamination particles. The purpose of this work is to provide a first investigation into the potential effects of the MR and fringe magnetic fields on the electro...

Sufficient skin dose needs to be delivered by a radiotherapy chest wall treatment regimen to ensure the probability of a near surface tumor recurrence is minimized. To simulate a chest wall treatment a hemicylindrical solid water phantom of 7.5 cm radius was irradiated with 6 MV x-rays using 20x20 cm2 and 10x20 cm2 fields at 100 cm source surface distance (SSD) to the base of the phantom. A sur...

PURPOSE Develop a technique to fabricate a 3D anthropomorphic breast phantom with known ground truth for image quality assessment of 2D and 3D breast x-ray imaging systems. METHODS The phantom design is based on an existing computer model that can generate breast voxel phantoms of varying composition, size, and shape. The physical phantom is produced in two steps. First, the portion of the vo...

Background: In head and neck radiotherapy, immobilization devices can affect dose delivery. In this study, a comprehensive end-to-end test was developed to evaluate the accuracy of radiotherapy treatment. Materials and Methods: An Alderson Radiation Therapy (ART) anthropomorphic phantom with EBT3 film was used to mimic the actual patient treatment process. Ten patients treated for nasopharyngea...

Cryogen Spray Cooling (CSC) is an auxiliary procedure that pre-cools the epidermis during Laser Dermatologic Surgery (LDS) to avoid non-specific epidermal thermal damage. During CSC, explosive atomization, inflight evaporation and droplet-substrate interaction affect heat extraction from the substrate. In order to understand the heat transfer mechanism of this complex process, we first study th...

Phantom and mouse experiments of time-domain fluorescence tomography were conducted to demonstrate the total light approach which was previously proposed by authors. The total light approach reduces the computation time to solve the forward model for light propagation. Time-resolved temporal profiles were acquired for cylindrical phantoms having single or double targets containing indocyanine g...