Endoscopic endonasal approach (EEA) is expected to be ideal for the paramedian ventral skull base meningiomas, allowing wide access to the ventral skull base regions and realizing early devascularization of the tumor without retraction of the brain. We searched clinical reports of EEA for skull base meningiomas, written in English language, published before October 2014, using the PubMed litera...

Olfactory groove schwannoma is a very rare tumor breaking through the skull base and orbit. The tumor may also extend to the subfrontal region intradurally. A case of olfactory groove schwannoma in a 35-year-old female, originating from the left olfactory groove with left proptosis, diplopia, supra-orbital mass, and gross intracranial extension is reported. The presence of bony scalloping on CT...

OBJECTIVES/HYPOTHESIS To provide a description of the techniques and limitations of nasoseptal flap takedown and reuse during second-stage and revision endoscopic skull base surgery and review the institutional experience with the use of this reconstructive technique. STUDY DESIGN : Case series. METHODS A retrospective analysis of cerebrospinal fluid (CSF) leak outcomes was performed for a ...

Introduction Over the past 20 years, magnetic resonance imaging (MRI) has advanced due to new techniques involving increased magnetic field strength and developments in coils and pulse sequences. These advances allow increased opportunity to delineate the complex skull base anatomy and may guide the diagnosis and treatment of the myriad of pathologies that can affect the skull base. Objectives ...

A review of patients with skull base osteosarcoma secondary to radiation (radiation-induced osteosarcoma: RIOS) of the pituitary tumor shows the mean survival of approximately 7 months (2 weeks-16 months). This warning prognosis seems to stem from two factors, 1) the anatomical complexity of the skull base for total resection of the tumor, and 2) standard adjuvant therapies for the tumor yet to...

A 42-year-old woman presented with symptoms of left-sided nasal obstruction, cerebrospinal fluid (CSF) rhinorrhea, and frequent sinus infections. Radiologic investigation revealed a tumor destructing the left cribriform plate and forming opacifications in the olfactory area. She had left-sided submucosal meningocele, deviating the septum to the right side. Intracranial involvement was not obser...

A recent chordoma cancer genotyping study reveals that the rs2305089, a single nucleotide polymorphism (SNP) located in brachyury gene and a key gene in the development of notochord, is significantly associated with chordoma risk. The brachyury gene is believed to be one of the key genes involved in the pathogenesis of chordoma, a rare primary bone tumor originating along the spinal column or a...

PURPOSE To describe the findings of skull base meningiomas on three-dimensional CT angiograms obtained with helical scanning and to evaluate the usefulness of this method. METHODS Fifteen patients who had a meningioma near the skull base were examined with helical CT after receiving an intravenous bolus injection of contrast material. RESULTS All meningiomas had either a honeycomb (12 patie...