This brief essay talks up the advantages of metal replicas for electron microscopy and explains why they are still the best way to image frozen cells in the electron microscope. Then it explains our approach to freezing, namely the Van Harreveld trick of "slamming" living cells onto a supercold block of metal sprayed with liquid helium at -269ºC, and further talks up this slamming over the alte...

Due to the increasing use of composite materials in high-speed planing craft prone frequent slamming, interaction between structural response and hydrodynamic loading, hydroelasticity, must be considered. In this work, a V-shaped wedge model with 20° deadrise angle was vertically dropped into calm water simulate typical hydroelastic slamming. With varied impact velocity flexural rigidity bottom...

Abstract The sensitivity of moving particle semi-implicit (MPS) simulations to numerical parameters is investigated in this study. Although the verification and validation (V&V) are important ensure accurate results, MPS has poor performance convergences with a time step size. Therefore, users need tune fit results into benchmarks. However, such tuning not always valid for other simulations...

This work evaluates the survivability of a point-absorbing wave energy converter at sea states along and inside 50-year environmental contour for selected-site in North Sea, by utilizing CFD simulations. Focused groups based on NewWave theory are used to model extreme waves. The numerical breaking waves have been previously predicted analytical criterion, showing that latter provides an accurat...

FcgammaR-mediated phagocytosis of IgG-coated particles is a complex process involving the activation of multiple signaling enzymes and is regulated by the inositol phosphatases PTEN (phosphatase and tensin homolog deleted on chromosome 10) and SHIP-1 (Src homology [SH2] domain-containing inositol phosphatase). In a recent study we have demonstrated that SHIP-2, an inositol phosphatase with high...

A semi-analytical model of hydroelastic slamming for two-dimensional symmetric flexible bodies is presented in this paper. The hydrodynamic loads are computed using the analytical Modified Logvinovich Model (MLM) with account elastic deflections body surface. described by modal approach. rigid and motions at same time together wetted part coupled problem impact reduced to a system nonlinear ord...

This survey discusses recent developments in the context of spherical designs and minimal energy point configurations on spheres. The recent solution of the long standing problem of the existence of spherical t-designs on S with O(td) number of points by A. Bondarenko, D. Radchenko, and M. Viazovska attracted new interest to this subject. Secondly, D. P. Hardin and E. B. Saff proved that point ...

This quarter we modified the database to account for the ship classification and ship counting guidance in the Secretary of the Navy’s Instruction 5030.8A [3]. First, we inserted four new fields: 1. 5030.8A Force Category – “Battleforce” or “Non-Battleforce.”1, 2 2. 5030.8A Ship Category – “Combatant Ship,” “Auxiliary Ship,” or “Combatant Craft.” 3. 5030.8A Ship Classification – For example: “W...