BACKGROUND CREBZF is a member of the mammalian ATF/CREB family of the basic region-leucine zipper (bZIP) transcription factors. Two isoforms of CREBZF have been identified from the alternative usage of initiation codons, SMILE (long isoform of CREBZF) and Zhangfei (short isoform of CREBZF). Until recently, the physiological function of CREBZF in mammalian reproductions has not been reported. ...

Purpose To evaluate transient corneal tissue healing and biomechanical changes between laser in situ keratomileusis (LASIK) and small incision lenticule extraction (SMILE) eyes. Methods In each patient, one eye underwent LASIK and the other underwent SMILE. Optical coherence tomography (OCT) and dynamic Scheimpflug imaging (Corvis-ST) was used to assess tissue healing and biomechanics, respec...

OBJECTIVE Smile esthetics has become a major concern among patients and orthodontists. Therefore, the aim of this study was: (1) To highlight differences in perception of smile esthetics by clinicians, orthodontists and laypeople; (2) To assess factors such as lip thickness, smile height, color gradation, tooth size and crowding, and which are associated with smile unpleasantness. METHODS To ...

We investigated persuasiveness as a social outcome of the ability to produce a deliberate Duchenne smile in a role-play task and of a participant’s use of a Duchenne smile while persuading someone in a live interaction. Participants were tasked with persuading an experimenter to drink a pleasant and unpleasant tasting juice as well as not drink a pleasant and unpleasant juice while being videot...

BACKGROUND Few studies have focused on the impact of malocclusion on lip - tooth relationships during smiling and speech. AIM To evaluate the impact of different malocclusions on lip - tooth relationships during smiling and speech, using video images. METHODS One hundred and three subjects with Class I (N = 31), Class II division 1 (N = 26), Class II division 2 (N = 16) and Class III malocc...

Smile is an object-oriented, equation-based, hybrid modeling and simulation environment. The focus of this paper is the extension (Smile/M) of the Smile system to Modelica, a new modeling language currently being defined in an international collaboration effort. An overview of this language, which may well become a quasi-standard in the simulation community, is given. Interfacing Smile to Model...

Timeless human esthetics implies a sense of beauty, a pleasing impulse, naturalness, and a youthful appearance relative to one’s age. The goal for esthetic treatment should be an enhanced but natural appearance that imparts a vibrant and believable appearance to the patient. This should be our goal in dental esthetics: a result that would be considered “bright, beautiful, but believable.” Nowad...

Purpose To investigate ex vivo potentially different corneal biomechanical properties after small-incision lenticule extraction (SMILE) versus LASIK for myopic correction. Methods Thirty human donor corneas were subjected to either myopic SMILE or femtosecond laser-assisted LASIK. Donor corneas were assigned to six investigative groups: Group A, -3.00 D (diopters) SMILE; Group B, -8.00 D SMIL...