Alginate hydrogel is a popular biologically inert material that is widely used in 3D bioprinting, especially in extrusion-based printing. However, the printed cells in this hydrogel could not degrade the surrounding alginate gel matrix, causing them to remain in a poorly proliferating and non-differentiating state. Here, we report a novel study of the 3D printing of human corneal epithelial cel...

In this study, a bioadhesive dosage form of clotrimazole was designed using a combination of bioadhesive polymers Carbopol 934P, sodium carboxymethyl cellulose and sodium alginate in different ratios. The bioadhesive strength was evaluated by measuring the force required to detach the tablets from porcine vaginal mucosal membrane. The strong interaction between polymer and mucus lining of the t...

The present work aims at developing mucoahesive tablets of ondansetron hydrochloride using bioadhesive polymers like carbopol-934, sodium alginate and gelatin. Tablets prepared by direct compression using different polymer with varying ratio were evaluated for hardness, friability, uniformity of weight, disintegration time, microenvironmental pH, bioadhesion and in vitro release. Hardness, fria...

We developed a novel fabrication technique of titania microspheres utilizing a robust external gelation method on an oil/hydrogel interface. By putting sodium alginate droplets on an interface between oil and Ca 2+ -loaded hydrogel, surfactant dissolved in oil forms amphiphilic bilayer. Water molecules and calcium ions transfer through this amphiphilic bilayer. As a result, alginate droplets sh...

background and aims. the most common method for alginate impression disinfection is spraying it by disinfecting agents, but some studies have shown that these impressions can be immersed, too. the aim of this study was to evaluate the dimensional stability of alginate impressions following disinfecting by spray and immersion methods. materials and methods. four common disinfecting agents (sodiu...

objective(s):   the production of nano-hydroxyapatite by two encapsulated bacterial strains was the goal of current research.  materials and methods:   serratia marcscens atcc 14756 and pseudomonas aeruginosa ptcc 1570 were used by two methods including encapsulated form in 2% (w/v) alginate sodium powder and inoculated form (10%) in nutrient broth medium containing alginate sodium blank beads....

Alginate encapsu lation of an atoxigen ic strain of Aspergillu s ̄ avus was studied in order to optimize encapsu lation of fungal inocula with alginic acid . Steriliza tion by autoclav ing is known to depolymerize sodium alginate . Buffered solution s (pH 5 7± 8) reduced this effect . Autoclaving the alginate solutio n with a ® ller/nutrien t further inhibite d the depolymerization reaction . Au...

Alginate lyases show great potential for industrial and medicinal applications, especially as an attractive biocatalyst for the production of oligosaccharides with special bioactivities. A novel alginate lyase, AlyH1, from the marine bacterium Vibrio furnissii H1, which has been newly isolated from rotten seaweed, was purified and characterized. The purified enzyme showed the specific activity ...

"Alginate/silica hybrid materials for immobilization of green microalgae Chlorella vulgaris for cellbased sensor arrays" (2014). Thin layers and patterned dot arrays of sodium alginate containing living microalgal cells were deposited onto glass carriers which were subsequently gelled using amino-functionalized silica sol to obtain reinforced alginate hydrogels. The resulting alginate/silica hy...

Bilayerd films were prepared by solvent casting technique using different concentration of two polymers namely, sodium alginate and pectin. The backing membrane was prepared by using sodium alginate. The drug containing layer was prepared by using pectin. Different concentrations of plasticizers and permeation enhancers were added. Prepared films were evaluated for surface properties, weight va...