Acute phosphate nephropathy or nephrocalcinosis is a tubulointerstitial nephropathy characterized by tubular calcium phosphate deposition - crystal nephropathy - and slowly progressive renal insufficiency during or following treatment with preparations containing sodium phosphate. We report a patient who developed nephrocalcinosis (crystal induced acute kidney injury) following the administrati...

Calcium ion binding with the anionic part of a molecule was replaced with various metal cations and their inhibitory effects on the replication of herpes simplex virus type 1 were evaluated. Replacement of calcium ion with sodium and potassium ions maintained the antiviral activity while divalent and trivalent metal cations reduced the activity. Depolymerization of sodium spirulan with hydrogen...

The role of the adrenal cortex in the pathogenesis of ascites has been studied in adrenalectomized clogs with thoracic inferior caval constriction. Discontinuation of hormone therapy resulted in a diuresis which demonstrates that adequate adrenocortical function or replacement therapy is essential for ascites formation during normal sodium (Na) intake. Evidence is presented in support of the th...

Sodium and water loss during, and replacement after, exercise-induced volume depletion was investigated in six volunteers volume depleted by 1.89 ± 0.17% (SD) of body mass by intermittent exercise in a warm, humid environment. Subjects exercised in a large, open plastic bag, allowing collection of all sweat secreted during exercise. For over 60 min beginning 40 min after the end of exercise, su...

Sodium-ion batteries (SIBs) are potential candidates for the replacement of lithium-ion to meet increasing demands electrical storage systems due low cost and high abundance sodium. Sodium superionic conductor (NASICON) structured materials have attracted enormous interest in recent years as electrode safer long-term performance SIBs electric energy smart grids. These a three-dimensional robust...

A patient with protracted vomiting was noted to have hyponatraemia and hypokalaemia on admission. Isotope dilution studies before treatment revealed profound body depletion of sodium, potassium and water. Treatment with potassium chloride tablets produced a simultaneous rise in serum sodium and potassium concentration without change in urine volume or osmolality, or body weight. Potassium deple...

Studies were conducted to examine the effects of adrenalectomy (ADX) and selective, physiological adrenal corticosteroid replacement on sodium and potassium transport by the superficial loop of Henle and distal tubule of rat kidney in vivo. In the loop of Henle, ADX inhibited sodium reabsorption by 33%. Whereas dexamethasone had no effect on reabsorption, aldosterone increased sodium transport ...

The effect of luminal sodium on intestinal glucose absorption at a variety of glucose concentrations was studied with a segmental perfusion technique in normal subjects. Uphill glucose transport was inhibited with sodium-free perfusions with either mannitol or Tris-HCl as the osmotic replacement of sodium (P < 0.01-P < 0.001). This effect did not appear to be the result of solvent drag, as incr...

The increased unidirectional sodium influx found when human erythrocytes are suspended in isotonic salt solutions containing bicarbonate ions as a replacement for chloride ions was examined. The increased sodium movement appears to have the transport characteristics of anion movement. Inhibitors of anion transport such as furosemide, fluorodinitrobenzene (FDNB), and 4-acetamido-4'-isothiocyano-...