نتایج جستجو برای: soleus muscle

تعداد نتایج: 328800  

Journal: :The Biochemical journal 1999
J W Ryder Y Kawano A V Chibalin J Rincón T S Tsao A E Stenbit T Combatsiaris J Yang G D Holman M J Charron J R Zierath

We have characterized the glucose-transport system in soleus muscle from female GLUT4-null mice to determine whether GLUT1, 3 or 5 account for insulin-stimulated glucose-transport activity. Insulin increased 2-deoxyglucose uptake 2.8- and 2.1-fold in soleus muscle from wild-type and GLUT4-null mice, respectively. Cytochalasin B, an inhibitor of GLUT1- and GLUT4-mediated glucose transport, inhib...

Journal: :The Journal of Physiology 2021

Key points Critical illness myopathy (CIM) is a frequently observed negative consequence of modern critical care. Chronic Janus kinase (JAK)/signal transducer and activator transcription activation impairs muscle size function prominent following mechanical ventilation. We identify pSTAT-3 in tibialis anterior CIM patients, before examining the potential benefits JAK1/2 inhibition an experiment...

Journal: :Bangladesh Critical Care Journal 2023

Dengue is the most common arboviral infection in world. hemorrhagic fever (DHF) presents withmanifestations like gum bleeding, melaena, menorrhagia, epistaxis, hemoptysis and sometimes bleeding into thirdspace all of which are well documented. Spontaneous intra-muscular hematoma a rare manifestation DHF; veryfew such cases have been reported so far. We report 25-year-old woman who was admitted ...

2013
Giulia Maria Camerino Sabata Pierno Antonella Liantonio Michela De Bellis Maria Cannone Valeriana Sblendorio Elena Conte Antonietta Mele Domenico Tricarico Sara Tavella Alessandra Ruggiu Ranieri Cancedda Yoshinobu Ohira Daniela Danieli-Betto Stefano Ciciliot Elena Germinario Dorianna Sandonà Romeo Betto Diana Conte Camerino Jean-François Desaphy

Pleiotrophin (PTN) is a widespread cytokine involved in bone formation, neurite outgrowth, and angiogenesis. In skeletal muscle, PTN is upregulated during myogenesis, post-synaptic induction, and regeneration after crushing, but little is known regarding its effects on muscle function. Here, we describe the effects of PTN on the slow-twitch soleus and fast-twitch extensor digitorum longus (EDL)...

Journal: :FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003
Bodvaël Fraysse Jean-François Desaphy Sabata Pierno Annamaria De Luca Antonella Liantonio Carlo I Mitolo Diana Conte Camerino

Using fura-2 and the manganese quenching technique, we show here that sarcolemmal permeability to cations (SP-Ca) of slow-twitch muscles is greater than that of fast-twitch ones. This appears to be related to a higher expression and/or activity of stretch-activated channels, whereas leak channel activities are similar. During hindlimb suspension (HU), we found highly correlated decreases in SPC...

Journal: : 2021

Еhe anabolic properties of a new composition leuzea and cranberry meal extracts in ratio 7:50, containing ecdisten ursolic acid, respectively, have been investigates on model isolated overload the skeletal muscle rats leg by method excision. Material methods. The experiment was conducted Wistar stock both sexes weighing 220–250 g. At beginning experiment, all animals underwent musculus gastrocn...

2012
Dorianna Sandonà Jean-Francois Desaphy Giulia M. Camerino Elisa Bianchini Stefano Ciciliot Daniela Danieli-Betto Gabriella Dobrowolny Sandra Furlan Elena Germinario Katsumasa Goto Martina Gutsmann Fuminori Kawano Naoya Nakai Takashi Ohira Yoshitaka Ohno Anne Picard Michele Salanova Gudrun Schiffl Dieter Blottner Antonio Musarò Yoshinobu Ohira Romeo Betto Diana Conte Stefano Schiaffino

The effect of microgravity on skeletal muscles has so far been examined in rat and mice only after short-term (5-20 day) spaceflights. The mice drawer system (MDS) program, sponsored by Italian Space Agency, for the first time aimed to investigate the consequences of long-term (91 days) exposure to microgravity in mice within the International Space Station. Muscle atrophy was present indistinc...

Journal: :The Biochemical journal 1987
B Leighton R A Challiss F J Lozeman E A Newsholme

1. Rats were treated with dexamethasone for 4 days before measurement of the rates of lactate formation [which is an index of hexose transport; see Challiss, Lozeman, Leighton & Newsholme (1986) Biochem. J. 233, 377-381] and glycogen synthesis in response to various concentrations of insulin in isolated incubated soleus and extensor digitorum longus muscle preparations. 2. The concentration of ...

Introduction: Sodium-dependent vitamin C transporter 2 (SVCT2) plays an important role in the transfer of ascorbic acid to slow-twitch fiber. The purpose of this study was investigating the effect of diabetes induction and exercise training on the level of ascorbic acid and muscle SVCT2 in rats. Methods: In this experimental study, 20 male Wistar rats were randomly divided into four groups (n=...

2016
Jin-Soo Kim Dong Hyun Yoon Hee-jae Kim Mi-jung Choi Wook Song

BACKGROUND Fibroblast growth factor-2 (FGF-2) protein level has been shown to be elevated in aged mice muscle compared to adult mice. It activates the satellite cell quiescence, which leads to satellite cell depletion and may accelerate aging process. The purpose of this study was to see the effect of resistance exercise on skeletal muscle FGF-2 protein level in aged mice. METHODS This study ...

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