Objective: To evaluate the effectiveness of adding hydrocortisone enema in traditional management Solitary rectal ulcers (SRU) pediatric patients. Study Design: Randomized Controlled Trial. Setting: Department Pediatric Gastroenterology, Children’s Hospital and The Institute Child’s Heath, Multan, Pakistan. Period: January, 2021 till December, 2021. Material & Methods: A total 52 children (...

There is a rising incidence of several sexually transmitted infections (STIs), many of which can present with proctitis. Causative organisms include Neisseria gonorrhoeae, Chlamydia trachomatis, herpes simplex virus, Treponema pallidum (syphilis), Giardia lamblia (giardiasis) and Entamoeba histolytica (amoebiasis). This paper outlines important clinical discriminators and key investigations to ...

In our opinion, the study did not reflect the true picture of SRUS in Saudi Arabia. The authors used pathology specimens for case identification. Depending only on histopathology will not provide the whole picture of the disease and might lead to missing some cases. An accurate diagnosis of SRUS is more commonly made based on a combination of symptoms, endoscopic findings, and histological appe...

Isolated or solitary ulcers of the large intestine are not associated with an underlying colitis and may be an incidental finding on screening colonoscopy or may present with abdominal pain, hematochezia, chronic gastrointestinal bleeding, and rarely, perforation [1]. Solitary rectal ulcer syndrome (SRUS) is a rare condition associated with chronic straining and abnormal defecation behavior, in...

Solitary rectal ulcer syndrome (SRUS) is an unusual disorder of childhood, which usually presents with rectal bleeding, mucous discharge, prolonged straining, tenesmus, and localized pain in the perineal area. After the first description by Cruveilhier, Madigan and Morson further detailed the clinical and pathologic features of SRUS in 1969. The pathogenesis of the syndrome is not well-understo...