BACKGROUND The sore throat pain model has been conducted by different clinical investigators to demonstrate the efficacy of acute analgesic drugs in single-dose randomized clinical trials. The model used here was designed to study the multiple-dose safety and efficacy of lozenges containing flurbiprofen at 8.75 mg. METHODS Adults (n=198) with moderate or severe acute sore throat and findings ...

• Headache, nausea and vomiting, malaise, dysphagia, and abdominal pain might be present. Sore throat decision rule The sore throat decision rule can identify both patients who are so likely to have GABHS that a confirmatory test is not needed and patients who are so unlikely to have GABHS that further testing is unrewarding. Using the rule will successfully identify most patients who need trea...