cases of sparganum mansoni , caused by the plerocercoid larva of the tapeworm s. mansoni , occur through­out the world, particularly in asian, middle eastern, and european countries. however, cases of infection with this parasite are rarely seen in japan. here, we present a case of a 61-year-old woman with a solitary subcutaneous nodule in left inner aspect of the thigh, from which a long, slen...

A highly specific antigenic protein of 31 kDa from plerocercoid of Spirometra mansoni (sparganum) was obtained by gelatin affinity and Mono Q anion-exchange column chromatography. The purified 31 kDa protein was subjected to N-glycan enzymatic digestion for structural analysis. The relative electrophoretic mobility was analyzed by SDS-PAGE, before and after digestion. On SDS-PAGE after enzymati...

Sparganosis is a parasitic disease in humans and animals caused by plerocercoid larvae (spargana) of the genus Spirometra. Spirometra erinaceieuropaei is the major causative agent of the disease in Asian countries. However, molecular evidence of the causative parasite species in animals remains lacking. A total of 19 spargana specimens were obtained from frogs, Hoplobatrachus rugulosus, collect...

Sparganosis is a parasitic disease in humans and animals caused by plerocercoid larvae (spargana) of the genus Spirometra. Spirometra erinaceieuropaei is the major causative agent of the disease in Asian countries. However, molecular evidence of the causative parasite species in animals remains lacking. A total of 19 spargana specimens were obtained from frogs, Hoplobatrachus rugulosus, collect...

caused by the larval form of an animal tapeworm of the genus Spirometra (1). The definite host is a carnivorous mammal, such as a dog or cat and intermediate hosts are a wide spectrum of vertebrates that include amphibians, reptiles, birds and mammals (2). Humans are usually a paratenic host (3). The route of infection is ingestion of raw meat of snakes or frogs, or drinking contaminated water ...

A 29-year-old Korean woman visited the Department of Surgery in MizMedi Hospital with a palpable itching mass on the right breast that had existed for the past 7 months. She had no history to eat either frogs or snakes, but had the history of drinking impure water. Sonography revealed a serpiginous hypoechoic tubular structure associated with partial fat necrosis in breast parenchymal layer and...

Sparganosis is a tissue invading helminthiasis infecting intermediate hosts, including humans. Strong immune responses are expected to occur in early phases of infection. Thus, we investigated cytokine expressions in splenic dendritic cells and in sera after experimental infection of mice. In splenic dendritic cells, TNF-α and IL-1β expression peaked at week 1 and week 3 post-infection (PI), re...