The purpose of the present investigation was to characterize and determine the number of NADPH-diaphorase positive neurons around the central canal in the rabbit spinal cord. These neurons are known to function as interneurons and are present in all spinal cord segments. They differ in shape of their bodies and in length and branching of their processes. The main differentiation was observed in...

Ivanenko, Y. P., R. E. Poppele, and F. Lacquaniti. Spinal cord maps of spatiotemporal alpha-motoneuron activation in humans walking at different speeds. J Neurophysiol 95: 602–618, 2006. First published November 9, 2005; doi:10.1152/jn.00767.2005. Functional MRI (fMRI) imaging of motoneuron activity in the human spinal cord is still in its infancy, and it will remain difficult to apply to walki...

Multiple sclerosis (MS) refers to the lesions that accumulate in the brain and spinal cord. Magnetic resonance imaging (MRI) is the most sensitive and versatile modality used to show changes in the tissues over time. There has been significant interest in evaluating the relationship between the brain atrophy and disease progression rather than the spinal cord atrophy. The cervical spinal cord h...

BACKGROUND AND PURPOSE In patients with intramedullary spinal cord metastases, the impact of MR imaging and clinical characteristics on survival has not been elucidated. Our aim was to identify MR imaging and clinical features with prognostic value among patients with intramedullary spinal cord metastases from a large retrospective series. MATERIALS AND METHODS The relevant MR imaging examina...

background and aims: neurons are injured under physical, chemical and pathological conditions. the effect of peripheral nervous system injuries may return as retrograde to the cell body of neurons in central nervous system resulting in brain and spinal cord degeneration. because of high content of camphor and borneol, achillea biebersteinii from asteracea family may be effective in prevention t...

Adult rats were subjected to midthoracic spinal cord transections. Three segments of spinal cord, each approximately 5 mm in length, were removed from each animal at intervals from 5 min to 48 h postlesion; one from the lesion site and one each immediately rostral and caudal to the transection. Total tissue calcium concentrations ([Ca]t) for each spinal cord segment were determined using atomic...

This study aims to test the value of diffusion tensor (DT) magnetic resonance (MR) imaging and fractional anisotropy (FA) mapping in detection of early cord dysfunction due to cervical spondilotic myelopathy before myelopathy is apparent on T2 weighted MR images Methods Totally 21 patients with neurological signs and symptoms of degenerative cervical stenosis enrolled in the study. None of the ...

Although the mammalian locomotor CPG has been localized to the lumbar spinal cord, the functional-anatomical organization of flexor and extensor interneurons has not been characterized. Here, we tested the hypothesis that flexor and extensor interneuronal networks for walking are physically segregated in the lumbar spinal cord. For this purpose, we performed optical recordings and lesion experi...