Although each statistical unit on which measurements are taken is unique typically there is not enough information available to account totally for its uniqueness. Therefore heterogeneity among units has to be limited by structural assumptions. One classical approach is to use random effects models, which assume that heterogeneity can be described by distributional assumptions. However, inferen...

Fundamental ecological processes, such as extrinsic mortality, determine population age structure. This influences disease spread when individuals of different ages differ in susceptibility or when maternal age determines offspring susceptibility. We show that Daphnia magna offspring born to young mothers are more susceptible than those born to older mothers, and consider this alongside previou...

The antitumoral effects of oncolytic viruses have generally been limited by inefficient spread of the viruses within infected tumors and by inefficient systemic delivery, particularly in preimmunized hosts. Tumor-selective poxviruses have biological characteristics that may overcome these limitations. Nevertheless, physical barriers within the tumor microenvironment, including the extracellular...

Recent research in the New England Journal of Medicine (NEJM) purports to show the existence of peer effects in the spread of obesity. Using a dataset of 5124 residents from Framingham, Massachusetts spanning the years 1971 to 2003, the authors show correlations between own weight gain and friends’ and relatives’ weight gain over this period. They find, furthermore, that these results are stron...

We investigated the capacity of internal border control to limit influenza spread in an emergent pandemic in the context of Australia, a country with a low-population density and geopolitical boundaries that may facilitate restrictions. Mathematical models were used to study the time delay between epidemics in 2 population centers when travel restrictions were imposed. The models demonstrated t...

In a metapopulation network, infectious diseases spread widely because of the travel of individuals. In the present study, we consider a modified metapopulation Susceptible-Infected-Removed (SIR) model with a latent period, which we call the SHIR model. In the SHIR model, an infectious period is divided into two stages. In the first stage, which corresponds to the latent period, infectious indi...

Few studies empirically estimate the effects of metropolitan growth on nonmetropolitan communities at a national scale. This paper estimates the growth effects of 276 MSAs on population in 1,988 nonmetropolitan communities in the United States from 2000 to 2007. We estimate the distance for growth spillovers from MSAs to nonmetropolitan communities and test the assumption that a single MSA infl...

In this work, we have studied the solvent effects on values of Gibbs free energy, enthalpy. entropy and dipolemoment in spread of solvents around anticancer thug of temreolomide that is an alighting agent. For thispurpose, the quantum mechanic calculations bawd on Hanrertnick theory at the STO-36/3-2Ith levels havebeen done. Moreover, we have compared resulted thermodynamic values in gas phase ...

This paper develops a model of depth and spread setting by a monopolistic dealer under asymmetric information to investigate the effect of imposing a transaction cost on the dealer’s quotes. Increasing the transaction cost affects the depth and the spread non-linearly. Under some distributional assumptions, when market conditions are favourable to the dealer, the spread responds less than propo...

Interactive simulation of point spread functions is an invaluable tool for evaluating optical designs. We present an interactive method for simulating the point spread function for designs that require diffraction and interference effects. These effects occure when the design contains apertures whose size approaches the wavelength of light, typically in the form of gratings or masks. Traditiona...