After removal of the 66 COOH-terminal amino acids from each of its two heavy chains by chymotrypsin digestion, Acanthamoeba myosin II forms only parallel dimers under conditions in which native myosin II forms bipolar filaments (Kuznicki, J., Cote, G. P., Bowers, B., and Korn, E. D. (1985) J. Biol. Chem. 260, 1967-1972). We have studied the solution structure of the chymotrypsin-cleaved myosin ...

We used 90 degrees light scattering, analytical ultracentrifugation, and electron microscopy to deduce that Acanthamoeba myosin-II minifilaments, composed of eight molecules each, assemble by a novel mechanism consisting of three successive dimerization steps rather than by the addition of monomers or parallel dimers to a nucleus. Above 200 mM KCl, Acanthamoeba myosin-II is monomeric. At low io...

We used 90 ° light scattering, analytical ultracentrifugation, and electron microscopy to deduce that Acanthamoeba myosin-II minifilaments, composed of eight molecules each, assemble by a novel mechanism consisting of three successive dimerization steps rather than by the addition of monomers or parallel dimers to a nucleus. Above 200 mM KCI, Acanthamoeba myosin-II is monomeric. At low ionic st...

The South African society continues to stagger under an immense wave of corruption in both the private and the public sectors. Corruption is the misuse of public office or a position of authority for private, material or social gain at the expense of other people. The aim of this investigation is to discuss the phenomenon from a moral point of view and to suggest moral directives and ways that ...

A numerical investigation was carried out to analyze the interactions between semi-active tandem flapping foils at various distances with a chord-based Reynolds number of 1100. Results indicate that distance less than 1.5 chord lengths and released in-phase, both exhibited terminal periodic motions nonzero mean stagger distance. In contrast, under other conditions, two ended up without stagger....

Tunnel FETs are a promising alternate to MOSFETs for low power design due to the ability to scale threshold voltage and hence supply voltage, without increase in OFF currents. However, they suffer from low ON currents. Demonstrated here is theenhancement in ION in arsenide–antimonide staggered-gap heterojunction (hetj) tunnel field-effect transistors (TFETs) by engineering the effective tunneli...