Ribosome stalling on mRNAs can decrease protein expression. To decipher ribosome kinetics at stall sites, we induced ribosome stalling at specific codons by starving the bacterium Escherichia coli for the cognate amino acid. We measured protein synthesis rates from a reporter library of over 100 variants that encoded systematic perturbations of translation initiation rate, the number of stall s...

A multidisciplinary research effort that combines aerodynamic modeling and gain-scheduled control design for aircraft flight at post-stall conditions is described. The aerodynamic modeling uses a decambering approach for rapid prediction of post-stall aerodynamic characteristics of multiple-wing configurations using known section data. The approach is successful in bringing to light multiple so...

In this short paper we briefly describe the results of analyzing a large-scale data set of actual YouTube stall patterns collected world-wide as part of Columbia University’s YouSlow project, and how we used it to create a simple model for generating realistic stalling patterns with a given number of stalls, a given average stall duration, and a pattern structure (describing the relative length...

Based on a detailed analysis of recent loss-of-control events, the Aircraft State Awareness Joint Safety Analysis Team has identified the need to develop algorithms and display strategies to provide control guidance for recovery from approach-to-stall or stall. In order to be effective, such guidance should enhance the pilot’s ability to execute the Federal Aviation Administration’s recommended...

Data prefetching is an effective way to hide memory latency. Current microprocessors allow multiple prefetch requests to overlap and provide a queue structure to track the outstanding requests. A prefetch request can either wait or be dropped when there is no available room in the queue. Recognizing the effectiveness and accuracy of the prefetches generated by the compiler, recent architectures...

Details of pressure distributions, on a two dimensional airfoil oscillating in pitch through stall, in a 0.8 0.8 m low-speed wind tunnel are presented. Pitching occurred about the airfoils quarter-chord axis. Pitch rate, Reynolds number, and oscillation amplitudes were varied to determine the effects on pressure and lift distributions. It was found that mean angle of attack and pitching amplitu...

We measure YouTube content delivery over IPv6 using ⇠100 SamKnows probes connected to dual-stacked networks representing 66 different origin ASes. Using a 34-months long (Aug 2014-Jun 2017) dataset, we show that success rates of streaming a stall-free version of a video over IPv6 have improved over time. We show that a Happy Eyeballs (HE) race during initial TCP connection establishment leads t...

The effects of ATP hydrolysis on actin polymerization-based force generation are calculated using a multistate two-state Brownian-ratchet model based on measured polymerization curves. For ensembles of filaments pushing against a rigid obstacle, the stall force per filament can be much less than the equilibrium ATP-actin stall force. PACS numbers: 87.15.Rn,87.17.Jj,87.16.Ac,87.15.Cc

Tests of a two-dimensional straight wing with a 10 per cent thick RAE 101 section have been made in a low-speed wind tunnel to check the validity of a criterion suggested by Owen and Klanfer for the type of bubble which will be formed when a laminar boundary layer separates from the surface of an aerofoil. The results confirm this hypothesis and show that if the boundary-layer Reynolds number b...