Abstract Background Antibiotic selection in children with periorbital and orbital infections is often empiric regimens vary widely among institutions their spectrum inclusion of anti-anaerobic anti-staphylococcal agents. Objectives Currently, there are no national clinical guidelines for antibiotic studies comparing commonly used infections. We aimed to determine the association initial outcome...

PURPOSE The purpose of this study was to perform molecular characterization of Staphylococcus aureus isolates causing a variety of eye infections from two major eye care hospitals in India. METHODS Twenty-four isolates from Aravind Eye Hospital, Madurai, India, and nine isolates from LV Prasad Eye Institute, Bhubaneswar, India, representing severe to nonsevere eye infections like microbial ke...

The immergence and dissemination of multidrug-resistant strains of Staphylococcus aureus in recent years have expedited the research on the discovery of novel anti-staphylococcal agents promptly. Bacteriophages have long been showing tremendous potentialities in curing the infections caused by various pathogenic bacteria including S. aureus. Thus far, only a few virulent bacteriophages, which d...

INTRODUCTION The present study evaluated biofilm-forming capacity and the presence of both icaA and icaD genes among staphylococcal strains isolated from catheter-related infections and blood culture. METHODOLOGY Ninety staphylococcal isolates, which included 45 strains of catheter infection origin and 45 strains of blood culture origin, were tested for their ability to produce biofilm using ...

BACKGROUND & OBJECTIVES Intravenous device (IVD) associated nosocomial blood stream infections due to staphylococci are major cause of morbidity and mortality. The present study was carried out to assess the frequency of staphylococcal IVD associated infections in a paediatric ward of a tertiary case hospital. Prevalence of resistance to commonly used antimicrobials in hospital acquired staphyl...

INTRODUCTION In Greece, fusidic acid and clindamycin are commonly used for the empiric therapy of suspected staphylococcal infections. METHODS The medical records of children examined at the outpatient clinics or admitted to the pediatric wards of the University General Hospital of Larissa, Central Greece, with community-associated staphylococcal infections from January 2003 to December 2009 ...

IgG antibodies directed against Staphylococcus aureus were examined by Western blotting in sera from 15 healthy individuals isolated for a year in Antarctica. Sera reacted with many staphylococcal antigens in whole-cell extracts and individuals showed unique and unchanging blot profiles. The IgG and IgM profiles of patients with deep-seated staphylococcal infections were also examined by Wester...

Abstract Identification of the receptors involved in innate immune recognition Staphylococcus aureus, a major cause morbidity and mortality humans, is essential to develop alternative strategies treat infections caused by antibiotic-resistant strains. In current study, we examine role endosomal TLRs, which sense presence prokaryotic-type nucleic acids, anti-staphylococcal host defenses using in...

Lysostaphin is a potent enzymatic anti-staphylococcal agent that lyses the cell walls of staphylococci in vitro. Studies described in the preceding paper demonstrated that lysostaphin rapidly killed staphylococci, was unaffected by human serum, and maintained its activity after prolonged incubation at body temperature.' Unlike the penicillins, lysostaphin was active in vitro against very large ...