Cardiorenal syndrome (CRS) frequently occurs in end-stage heart failure patients waiting for transplantation (HT). Decision-making regarding simultaneous and kidney is an unresolved issue these patients. We investigated clinical factors associated with renal outcome after HT. A total of 180 who received HT from 1996 to 2015 were included. Factors early post-HT chronic disease (CKD, estimated gl...

introduction Hemorrhagic transformation (HT) of ischemic infarcts is one of the main complications of thrombolytic therapy for acute stroke. HT also occurs frequently in untreated stroke patients, but it is typically less severe and often not associated with a worsening of clinical symptoms. Although HT is clearly an area of clinical concern, relatively few imaging studies have investigated HT ...

The functional roles of the medullary raphé, and specifically 5-HT neurons, are not well understood. It has previously been stated that the role of 5-HT has been so difficult to understand, because "it is implicated in virtually everything, but responsible for nothing"(Cowen PJ. Foreword. In: Serotonin and Sleep: Molecular, Functional and Clinical Aspects, edited by Monti JM, Prandi-Perumal SR,...

The link between the anti-Parkinsonian drug L-3,4-dihydroxyphenylalanine (L-DOPA) and the serotonergic (5-HT) system has been long established and has received increased attention during the last decade. Most studies have focused on the fact that L-DOPA can be transformed into dopamine (DA) and released from 5-HT terminals, which is especially important for the management of L-DOPA-induced dysk...

BACKGROUND AND OBJECTIVES Components of complementary and alternative medicine are increasingly being implemented at academic medical centers. These approaches include therapeutic touch or healing touch (HT), an energy-based therapy using light touch on or near the body. Limited data exist regarding complementary and alternative medicine use at children's hospitals. The aim of this study was to...

This review summarizes the current status, operating principles, and recent advances in high-temperature polymer electrolyte membranes (HT-PEMs), with a particular focus on developments, technical challenges, commercial prospects of HT-PEM fuel cells. A detailed most research activities has been covered by this work, major state-of-the-art concepts describing proton conductivity degradation mec...

Postoperative nausea and vomiting (PONV) remains a significant problem in modern anesthetic practice, with an incidence in high-risk groups of up to 80%. In addition to being unpleasant and distressing for the patient, PONV has the potential to adversely affect patient and surgical outcomes. Advances in PONV prophylaxis over recent years include using non-pharmacological means to reduce baselin...

This paper is a specialized literature review of the pharmacology of serotonin, that focuses on pharmacodynamics. The main aspects discussed here are the metabolism and transport of serotonin, along with the structure and functions of 5-HT receptors and their clinical implications. We also included the substances that influence the serotonin neurotransmission and the autacoid function, which ma...

OBJECTIVE Thyroid disorders, especially Hashimoto's thyroiditis (HT), are observed significantly more often in patients with polycystic ovary syndrome (PCOS) than in the general population - approximately 27% and 8%, respectively. This is extremely important in young women, because both disorders are connected with fertility problems. As HT and PCOS occur together, fertility problems may become...

As soon as in the 1960's, the role of serotonin (5-Hydroxytryptamin, 5-HT) in psychiatric disorders was realized, which was further substantiated by several lines of evidence amounting to a huge body of knowledge. The indolamine 5-HT belongs to the class of monoamine transmitters and can be found in the serotonergic neurons of the raphe nuclei in the brain stem. In the periphery, it is mainly p...