Stereotactic radiosurgery (SRS) provides excellent control in the treatment of brain metastases (BM). The use of newer, targeted and immunotherapy treatments have resulted in improved overall survival in patients even with an extensive metastatic disease. Hence, it is increasingly important to consider the potential for late toxicities like radiation-induced necrosis (RN) of the brain. We prese...

OBJECTIVES/HYPOTHESIS A relation between conventional radiotherapy and the development of intracranial neoplasma is well known, but radiation-associated tumor following stereotactic radiotherapy of vestibular schwannoma is underestimated. In this article we will study this relation by doing a complete literature review on all the malignant intracranial tumors that appeared following radiosurger...

Despite advances in the fields of surgery, chemotherapy and radiotherapy, the prognosis for high-grade glioma (HGG) remains unsatisfactory. The majority of HGG patients experience disease recurrence. To date, no standard treatments have been established for recurrent HGG. Repeat surgery and chemotherapy demonstrate moderate efficacy. As recurrent lesions are usually located within the previousl...

Stereotactic Radiosurgery (SRS) is a non-invasive technique for the delivery of highly focused ionizing radiation with extreme precision. It is used in neurosurgical practice as a less invasive means of targeting benign and malignant brain tumors, vascular malformations, and functional disorders. Its ability to elicit a desired response (e.g. tumor cell death) with minimal effect on normal surr...

Whole brain radiation therapy has been the traditional treatment of choice for patients with multiple brain metastases. Although stereotactic radiosurgery is widely accepted for the management to up to 4 brain metastases, its use is still controversial in cases of 5 or more brain metastases. Randomized trials have suggested that stereotactic radiosurgery alone is appropriate in up to 4 metastas...

A section of this issue of TCRT focuses on four articles dealing with technological advances in brain and spine radiosurgery. With the evolution of radiation technology to allow for high precision image-guided radiotherapy as an integrated part of mainstream linear accelerators, the practice of stereotactic radiosurgery (SRS) is commonly applied to the brain and is rapidly developing as an attr...

During stereotactic body radiotherapy, high radiation dose (~60 Gy) is delivered to the tumour in small fractionation regime. In this study, the dosimetric characteristics were studied using radiochromic film during respiratory-gated and non-gated lung stereotactic body radiotherapy (SBRT). Specifically, the effect of respiratory cycle and amplitude, as well as gating window on the dosimetry we...

Abstract Stereotactic radiosurgery and stereotactic body radiation therapy have been increasingly utilized in oncology to treat early stage tumors, metastatic targets, retreatment of relapsed diseases due their efficiency, treatment effect, cost effectiveness over the past two decades. both demand high specifications for delivery machines, as they deliver doses with fewer fractions higher per f...

A patient presented with symptoms and signs of raised intracranial pressure and increasing focal deficit 13 months after stereotactic radiosurgical treatment of an arteriovenous malformation (AVM). Computed Tomography (CT) showed a mass lesion at the site of the previous abnormality typical of radiation necrosis, but with features identical to those of a malignant neoplasm. Biopsy confirmed cer...

Recent technological advances in photon-RT have allowed an improvement in targeting accuracy, dose escalation, delivery of multiple large fractions (hypofractionated stereotactic radiation therapy HSRT) or single fraction stereotactic ablative radiation therapy (radiosur‐ gery SRS). Radiosurgery delivers a single large dose with very steep dose fall-off outside the lesion to very small volumes ...