The development and scope of stereotactic radiosurgery is described. The technique, which combines well with the latest diagnostic methods, has already proved a safe and effective way of treating inaccessible cerebral lesions and in particular small arteriovenous malformations, acoustic neuroma and the solid component of craniopharyngioma, as well as playing an increasingly useful role in the t...

Treatment of arteriovenous malformations (AVMs) is complicated because of many factors including increasing size, eloquent location, and risk of unacceptable neurological deficits. Each of the treatment modalities, microsurgery, embolization, and stereotactic radiosurgery (SRS), has its pros and cons. Surgery and embolization are limited by location, size, and afferent and efferent vessel anato...

Brain metastases management is still controversial even though many trials are trying to define the respective roles of neurosurgery, whole-brain radiotherapy, single-dose stereotactic radiotherapy and fractionated stereotactic radiotherapy. In this article, we review data from trials that examine the role of radiosurgery and fractionated stereotactic radiotherapy in the management of brain met...

Evaluation of the Three Dimensional Localization Accuracy Using Cone-Beam Computed Tomography in Stereotactic Radiosurgery

BACKGROUND Stereotactic radiosurgery (SRS) and stereotactic radiotherapy (SRT) are highly conformal, high-dose radiation treatment techniques used to treat people and dogs with brain tumors. OBJECTIVES To evaluate the response to SRS- and SRT-treated tumors using volume and perfusion variables and to measure the survival times of affected dogs. ANIMALS Prospective study of 34 dogs with evid...

Background: Radiosurgery is a focal brain irradiation technique that delivers, usually in a single session, high dose of ionizing radiation. The presence of lateral electronic disequilibrium and steep dose gradients in small fields demands special attention to the selection of a suitable detector with respect to its size, composition and response. Materials and Methods : Small circular fields w...

Background: Brain necrosis (RN) is a common radiotherapy sequela for brain metastases. Bevacizumab identified as therapeutic strategy RN. This study aimed to the clinical and radiobiological impacts on efficacy of in treating RN following stereotactic radiosurgery (SRS)

INTRODUCTION Stereotactic brain radiosurgery provides good local control in patients with limited brain metastases. A newly developed frameless system allows pain-free treatment. We reviewed the effectiveness of this frameless stereotactic brain radiosurgery and identified prognostic factors that may aid better patient selection. METHODS Medical records of patients with brain metastases treat...

OBJECTIVE Benign and malignant tumors of the spine significantly impair the function and quality of life of many patients. Standard treatment options, including conventional radiotherapy and surgery, are often limited by anatomic constraints and previous treatment. Image-guided stereotactic radiosurgery using the CyberKnife system (Accuray, Inc., Sunnyvale, CA) is a novel approach in the multid...

Purpose/Objective(s): To establish a dose-volume response relationship for brain metastases treated with single-fraction robotic stereotactic radiosurgery and identify predictors of local control. MATERIALS/METHODS We reviewed a prospective institutional database of all patients treated for intact brain metastases with stereotactic radiosurgery alone using the CyberKnife robotic radiosurgery ...